急性冠状动脉综合征患者缺血修饰白蛋白水平与冠状动脉病变程度的相关性研究

发布时间：2018-04-20 16:21

本文选题：急性冠状动脉综合征 + 缺血修饰白蛋白　；参考：《中国医科大学学报》2017年11期

【摘要】：目的探讨急性冠状动脉综合征(ACS)患者缺血修饰白蛋白(IMA)水平与冠状动脉病变程度的相关性。方法入选ACS患者51例。所有患者入院后均进行冠状动脉造影检查及冠状动脉粥样硬化性心脏病规范治疗,收集冠状动脉造影结果并计算Gensini评分,检测IMA水平。同期选取健康志愿者10例作为对照组。结果冠状动脉病变组IMA水平均高于对照组(P0.05);但各冠状动脉病变组组间比较IMA水平均无统计学差异。IMA水平与其Gensini评分无相关性;但Gensini评分中度组TIMI血流3级比例低。结论 ACS患者IMA水平升高,但IMA水平与冠状动脉病变程度无相关性,IMA不能准确反映冠状动脉病变程度,IMA水平升高提示心肌缺血处于不稳定状态。
[Abstract]:Objective to investigate the correlation between the level of ischemic modified albumin (IMA) and the degree of coronary artery disease in patients with acute coronary syndrome (ACS). Methods 51 patients with ACS were selected. All patients were treated with coronary angiography and coronary atherosclerotic cardiopathy after admission. The results of coronary angiography were collected and Gensi was calculated. The level of IMA was measured by Ni. 10 healthy volunteers were selected as control group at the same time. The results showed that the level of IMA in coronary artery disease group was higher than that of the control group (P0.05), but there was no statistical difference between the.IMA level and the Gensini score between the groups of coronary artery lesions, but the proportion of TIMI blood flow in the moderate group of Gensini score was low. The level of IMA in ACS patients was elevated, but there was no correlation between the level of IMA and the degree of coronary artery disease. IMA could not accurately reflect the degree of coronary artery disease. The increase of IMA level suggested that the myocardial ischemia was in the unstable state.

【作者单位】：民航总医院心内科;中国医科大学附属第一医院老年病科;中国医科大学附属第一医院心内科;
【基金】：沈阳市科学技术计划(F16-206-9-06)
【分类号】：R541.4

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