合并快静息心率的高血压患者的临床特征分析

发布时间：2018-05-12 21:31

  本文选题：高血压 + 心率　； 参考：《中国循环杂志》2017年07期

【摘要】：目的:探究合并快静息心率的高血压患者的临床特征及其常见临床合并症情况。方法:本研究回顾性分析了2000年山东青岛港研究和2005年河南信阳研究纳入的静息心电图资料完整的18岁以上社区人群,包括高血压与非高血压患者。收集患者的临床合并症(包括糖尿病、冠心病、高脂血症、脑卒中等)、实验室检查结果、心电图静息心率(RHR)、体重指数(BMI)、腰臀比以及诊室血压。结果:纳入受试者18 183例,61.6%为男性,平均年龄(45.2±12.7)岁,高血压患者6 763例。高血压患者的静息心率明显高于正常血压人群[(73.5±11.6)次/min vs(70.6±9.6)次/min,P0.001],合并快静息心率的患者比例显著高于非高血压者(14.5%vs 6.4%,P0.001)。在高血压患者中,与正常静息心率的患者相比,合并快静息心率的患者年龄更大[(51.8±11.2)岁vs(53.9±12.2)岁,P0.001),体重指数更低([26.4±3.4)kg/m~2 vs(25.8±3.6)kg/m~2,P0.001],3级高血压患者比例更高(59.0%vs 68.2%,P0.001),空腹血糖[(5.6±1.5)mmol/L vs(6.0±2.4)mmol/L,P0.001]、甘油三酯([1.7±1.3)mmol/L vs(2.0±1.8)mmol/L,P0.001]及低密度脂蛋白胆固醇水平更高([3.1±0.8)mmol/L vs(3.2±0.9)mmol/L,P=0.001)],合并糖尿病(3.9%vs 6.6%,P=0.007)和脑卒中(8.3%vs 11.1%,P=0.005)的比例高。多因素回归分析校正传统危险因素后发现,快静息心率与高血压患者的脑卒中风险呈正相关(OR=1.306,95%CI:1.021~1.671)。结论:高血压人群中快静息心率比例显著高于正常血压人群。合并快静息心率的高血压患者年龄更大,体重指数更低,多为3级高血压患者,且多合并糖尿病、脑卒中。快静息心率增加高血压患者的脑卒中风险。
[Abstract]:Objective: to investigate the clinical features and common clinical complications of hypertensive patients with fast resting heart rate. Methods: this study retrospectively analyzed the community population over 18 years old with complete resting ECG data, including hypertension and non-hypertension, which were included in the study of Qingdao Port, Shandong Province in 2000 and Xinyang study in Henan Province in 2005. Clinical complications (including diabetes, coronary heart disease, hyperlipidemia, stroke, etc.), laboratory findings, resting heart rate (RHRG), body mass index (BMI), waist-to-hip ratio (WHR), and laboratory blood pressure were collected. Results: 18 183 subjects were male (61.6%), with an average age of 45.2 卤12.7 years, and 6 763 patients with hypertension. The resting heart rate of hypertensive patients was significantly higher than that of normal blood pressure group [73.5 卤11.6times / vs(70.6 卤9.6times / r / min P0.001], and the proportion of patients with rapid resting heart rate was significantly higher than that of non-hypertensive patients (14.5vs 6.4g / P 0.001g / min). In patients with hypertension, compared with patients with normal resting heart rates, 鍚堝苟蹇�闈欐伅蹇冪巼鐨勬偅瑁�

本文编号：1880234