探讨老年人骨质疏松与动脉硬化风险之间的关系

发布时间：2018-06-03 09:24

本文选题：老年人 + 骨质疏松　；参考：《中国骨质疏松杂志》2017年03期

【摘要】：目的通过对老年人骨密度、T值与肱-踝脉搏波传导速度关系的分析,探讨老年人骨质疏松与动脉硬化的相关性。方法对97例老年高血压、冠心病患者采用双能X射线骨密度仪进行腰椎、股骨颈和前臂的骨密度测试,采用动脉硬化仪测定患者的肱-踝脉搏波传导速度(brachial-ankel pulse wave velocity,ba PWV),采用全自动生化仪测定患者的生化指标。根据T值将患者分为骨量正常组、骨量减少组和骨质疏松组,根据ba PWV将患者分为动脉硬化组和非动脉硬化组。结果骨量正常患者、骨量减少患者和骨质疏松患者的ba PWV依次增高,动脉硬化患者的BMD值和T值明显低于非动脉硬化患者,差异均有统计学意义(P0.05),动脉硬化患者与非动脉硬化患者之间、不同程度骨质疏松患者之间的性别分布、BMI、Ca、P、TC、TG、HDL-C、LDL-C、Apo A、Apo B比较差异无统计学意义(P0.05)。患者的T值、BMD分别与ba PWV呈负相关关系(r=-0.954、-0.923,P0.05)。结论老年人的骨质疏松和动脉硬化之间存在一定的作用关系。早期测定骨密度对骨质疏松的老年人群采取干预措施可能对老年人动脉硬化具有一定的防治效果。
[Abstract]:Objective to study the correlation between osteoporosis and arteriosclerosis by analyzing the relationship between bone mineral density (BMD) T value and brachial-ankle pulse wave conduction velocity in the elderly. Methods the bone mineral density of lumbar vertebrae, femoral neck and forearm were measured by dual energy X-ray absorptiometry in 97 elderly patients with hypertension and coronary heart disease. Brachial-ankle pulse wave velocity (brachial-ankel pulse wave velocityba PWV) was measured by arteriosclerosis instrument and biochemical index was measured by automatic biochemical instrument. According to T value, the patients were divided into normal group, reduced group and osteoporosis group. According to BA PWV, the patients were divided into arteriosclerosis group and non-arteriosclerosis group. Results the BA PWV of the patients with normal bone mass, the patients with osteopenia and the patients with osteoporosis increased in turn, and the BMD and T values of the patients with arteriosclerosis were significantly lower than those of the patients with non-arteriosclerosis. There was no significant difference in sex distribution between patients with arteriosclerosis and non-arteriosclerosis patients, and between patients with different degrees of osteoporosis. There was no significant difference in the sex distribution between the two groups (P0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, P 0. 05, respectively). There was a negative correlation between T value and ba PWV. Conclusion there is a certain relationship between osteoporosis and arteriosclerosis in the elderly. Early measurement of bone mineral density may be effective in preventing and curing atherosclerosis in the elderly with osteoporosis.
【作者单位】：南阳医学高等专科学校内科教研室;内蒙古医科大学附属医院;
【分类号】：R580;R543.5

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