原发性高血压患者晨峰血压与血尿酸的相关性

发布时间：2018-06-17 13:04

本文选题：原发性高血压 + 晨峰血压　；参考：《中国老年学杂志》2017年07期

【摘要】：目的探讨原发性高血压(EH)患者晨峰血压(MBPS)与血尿酸(UA)的关系。方法入选2014年11月至2015年12月住院的EH患者为研究组(n=195),另入选同期健康体检者为正常对照组(n=88)。对研究组行24 h动态血压监测,根据监测结果将研究组分为晨峰组(n=93)、非晨峰组(n=102);禁食12 h后于动态血压监测当天早晨行UA、空腹血糖(FPG)、胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDLC)、低密度脂蛋白胆固醇(LDL-C)、尿素氮、肌酐(SCr)检测,并记录临床数据。结果研究组UA高于正常对照组,晨峰组高于非晨峰组(P0.05)。相关分析提示MBPS与UA呈正相关(r=0.384,P0.01)。多元线性回归分析显示UA水平与MBPS呈独立正相关(B=0.05,P0.01)。结论 UA与高血压密切相关,并且与MBPS呈正相关,是晨峰血压的一个独立影响因素。
[Abstract]:Objective to investigate the relationship between morning peak blood pressure (MBPSs) and serum uric acid (UAA) in patients with essential hypertension (EH). Methods EH patients in the study group from November 2014 to December 2015 were enrolled in the study group. 24 h ambulatory blood pressure monitoring was performed in the study group. According to the monitoring results, the study group was divided into morning peak group (n = 93), non-morning peak group (n = 102), fasting for 12 h, UAA, fasting for 12 hours, fasting blood pressure monitoring, fasting blood glucose, FPG, TC, TG, HDLC, LDL-C, urea nitrogen. Creatinine was detected and clinical data were recorded. Results the UA in the study group was higher than that in the normal control group, and the morning peak group was higher than that in the non morning peak group (P 0.05). The correlation analysis indicated that MBPS and UA were positively correlated with 0.384 (P 0.01). Multiple linear regression analysis showed that there was an independent positive correlation between UA level and MBPS. Conclusion UA is closely related to hypertension and positively correlated with MBPS, which is an independent factor of morning peak blood pressure.
【作者单位】：郑州大学第二附属医院心内科;
【分类号】：R544.11

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