累积心率暴露对臂踝脉搏波传导速度的影响

发布时间：2018-07-21 18:19

【摘要】：目的探讨累积心率暴露(cum HR)与臂踝脉搏波传导速度(ba PWV)的关系。方法选择开滦研究人群中卒中队列和老年人群队列7904例组成观察人群,最终纳入研究队列的为5153例。根据cum HR将研究对象进行四分位分组。采用偏相关分析cum HR与ba PWV的相关性,多因素线性回归和多因素Logistic回归分析cum HR对ba PWV的影响。结果随着cum HR的增加,平均ba PWV水平和ba PWV≥1400 cm/s的检出率均呈上升趋势。偏相关分析结果表明,cum HR与ba PWV呈正相关(r=0.35,P0.05);校正了年龄、性别后cum HR与ba PWV仍呈正相关(r=0.24,P0.05)。多因素线性回归分析显示,cum HR每增加1次/分,ba PWV增加1.071 cm/s。Logistic回归分析表明,校正了其他混杂因素后,与cum HR第一分位组相比,cum HR第二分位组、第三分位组、第四分位组均是ba PWV≥1400 cm/s的危险因素,OR值(95%CI)分别为1.432(1.121~1.829)、1.738(1.371~2.204)、2.475(1.949~3.143)。结论 cum HR与ba PWV呈正相关关系。cum HR是脉搏波传导速度增加的危险因素。
[Abstract]:Objective to investigate the relationship between cumulative heart rate exposure (cum HR) and brachial pulse wave velocity (PWBA V). Methods 7904 stroke cohorts and elderly cohorts were selected from Kailuan study group and 5153 cases were included in the study cohort. The subjects were divided into quartiles according to cum HR. The correlation between cum HR and ba PWV was analyzed by partial correlation analysis, and the influence of cum HR on ba PWV was analyzed by multivariate linear regression and multivariate logistic regression analysis. Results with the increase of cum HR, the average BA PWV level and the detection rate of BA PWV 鈮，

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