高血压患者盐摄入量与夜间血压和早期肾损害的关系
发布时间:2018-07-24 15:02
【摘要】:目的:通过对24h尿钠的检测,判断个体每日摄盐量,并探讨高血压患者盐摄入量与夜间血压水平和早期肾损害的关系。方法:选择2016年5月至2017年4月遵义医学院附属医院高血压门诊就诊的初诊未治疗高血压患者180例,其中男性91例,女性89例。年龄18~83岁。根据日均摄盐量分为A组(5g,n=145)与B组(≤5g,n=35)。用Spearman相关分析盐摄入量与早期肾损害的关系,多元线性回归和偏相关分析影响早期肾损害的危险因素。结果:男性高血压患者日均摄盐量高于女性高血压患者。A组患者早期肾损害检出率为31.7%,B组患者早期肾损害检出率为8.6%。日均摄盐量与白昼平均收缩压、白昼平均舒张压、夜间平均收缩压、夜间平均舒张压均呈正相关(r=0.200,P0.05;r=0.225,P0.05;r=0.207,P0.01;r=0.273,P0.01);与24h尿微量白蛋白呈正相关(r=0.350,P=0.000)。白昼平均收缩压、白昼平均舒张压、夜间平均收缩压、夜间平均舒张压与24h尿微量白蛋白均呈正相关(r=0.298,P0.01;r=0.232,P0.01;r=0.228,P0.01;r=0.234,P0.01)。多元线性回归、偏相关分析提示日均摄盐量、24h尿钠/尿钾、心率及夜间平均舒张压是早期肾损害的影响因素[β=7.717(95%CI 5.934~9.500),P0.01;β=-6.234(95%CI-9.677~-2.790),P0.01;β=0.697(95%CI 0.154~1.241),P0.05;β=0.662(95%CI 0.032~1.293),P0.05]。结论:日均摄盐量与夜间血压水平呈正相关,是高血压患者早期肾损害的影响因素。
[Abstract]:Objective: to determine the daily salt intake and the relationship between salt intake and nocturnal blood pressure and early renal damage in patients with hypertension. Methods: from May 2016 to April 2017, 180 patients (91 males and 89 females) with untreated hypertension were selected from outpatient clinic of affiliated Hospital of Zunyi Medical College. The age is 1883. According to the daily average salt intake, group A (5 g) and group B (鈮,
本文编号:2141753
[Abstract]:Objective: to determine the daily salt intake and the relationship between salt intake and nocturnal blood pressure and early renal damage in patients with hypertension. Methods: from May 2016 to April 2017, 180 patients (91 males and 89 females) with untreated hypertension were selected from outpatient clinic of affiliated Hospital of Zunyi Medical College. The age is 1883. According to the daily average salt intake, group A (5 g) and group B (鈮,
本文编号:2141753
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