冠脉内替罗非班联合血栓抽吸在急性ST段抬高心梗急诊介入的应用研究

发布时间：2018-08-22 18:20

【摘要】：目的探讨冠脉内替罗非班联合血栓抽吸在急性ST段抬高心梗急诊介入的应用。方法选择2012年5月至2013年12月收治的102例急性ST段抬高心梗患者,按治疗方式分作对照组与研究组,每组51例,对照组予以冠脉内替罗非班治疗,研究组基于对照组予以联合血栓抽吸治疗,比较两组心肌灌注情况,肌酸激酶同工酶(CK-MB),肌钙蛋白I(c Tn I),脑钠肽(BNP),血管内皮功能,和不良反应发生情况。结果研究组ST段恢复率、心肌MBG3级、TIMI血流3级率高于对照组(P0.05)。研究组CK-MB、c Tn I、BNP低于对照组(P0.05)。研究组血管内皮功能优于对照组(P0.05)。两组不良反应率比较无差异(P0.05)。结论冠脉内替罗非班联合血栓抽吸在急性ST段抬高心梗急诊介入中的效果肯定,能够改善心肌再灌注,缓解心肌损伤。
[Abstract]:Objective to investigate the application of coronary endofiloban combined with thrombotic aspiration in acute St segment elevation myocardial infarction. Methods 102 patients with acute ST-segment elevation myocardial infarction admitted from May 2012 to December 2013 were divided into two groups: control group (n = 51) and study group (n = 51). The study group was treated with combined thrombotic aspiration based on the control group. Myocardial perfusion, creatine kinase isoenzyme (CK-MB), cerebral natriuretic peptide (BNP), endothelial function, and adverse reactions were compared between the two groups. Results the recovery rate of St segment and the blood flow rate of MBG3 grade TIMI in the study group were higher than those in the control group (P 0.05). The BNP of CK-MBN c TN in the study group was lower than that of the control group (P 0.05). The vascular endothelial function in the study group was better than that in the control group (P0.05). There was no difference in adverse reaction rate between the two groups (P0.05). Conclusion Coronary endofilofiban combined with thrombotic aspiration is effective in acute St segment elevation myocardial infarction, which can improve myocardial reperfusion and alleviate myocardial injury.
【作者单位】：广西壮族自治区人民医院;
【基金】：广西科技厅科技攻关项目,项目编号:1298003-3-7
【分类号】：R542.22

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