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aVR导联T波方向对行急诊PCI术的急性前壁心肌梗死患者的预测价值

发布时间:2018-09-08 12:57
【摘要】:目的:探讨行急诊PCI治疗的急性前壁心肌梗死患者入院心电图aVR导联T波方向与住院期间转归的关系。 方法:随机选取我院2011年1月至2012年12月行急诊PCI术的急性前壁心肌梗死患者75人(平均年龄59.5±11.6岁,男性59人)进行回顾性分析。入选标准:①症状发生12小时内(典型的胸痛持续时间30分钟,含服硝酸甘油无效)行急诊PCI术;②急性前壁心肌梗死心电图特征或动态改变,ST段测量为J点后60ms,至少2个连续心电图导联ST段改变幅度≥2mm;③血清肌钙蛋白I(cTnI)的动态演变。排除标准:①无血管成形术指征及冠脉搭桥手术史;②严重瓣膜疾病、心室肥厚、其他部位心室壁心肌梗死、严重的电解质紊乱、左或右束支传导阻滞、室内传导阻滞、起搏心律、预激综合征、心房扑动、心房纤颤致ST段不能准确测量者。根据入院心电图aVR导联T波方向将患者分为T波直立组(≥0mm,N=24,A组)和T波倒置组(0mm,N=51,B组)。详细记录两组患者的一般临床资料、肌酸激酶同工酶、肌钙蛋白I、aVR导联ST段水平、左心室射血分数、冠脉造影结果、非死亡患者住院时间和住院期间严重心血管事件(心肌再梗死、恶性心律失常、严重心力衰竭、心源性休克及心源性死亡)等资料。应用SPSS21.0统计软件进行统计分析,以p0.05为差异具有统计学意义。 结果:行急诊PCI术的急性前壁心肌梗死患者中,aVR导联T波直立组左室射血分数更低(A组45.04%±16.247%,B组:51.59%±10.566%,p0.05),排除死亡患者后A组的住院时间更长(A组9.68±2.709天,B组7.55±2.424天,p0.05)。多支病变患者共38例(A组17例、B组21例),A组多支病变患者比例明显高于B组(A组70.8%、B组41.2%,p0.05),敏感性、特异性和准确率分为44.7%、81.8%和62.6%。住院期间发生严重心血管事件的患者共38例(A组11例、B组5例,p0.05),A组较B组患者住院期间严重心血管事件发生率更高(A组45.8%、B组9.8%,p=0.000),敏感性、特异性和准确率分为68.8%、78.0%和76.0%。住院期间死亡在A、B两组间差异无统计学意义(p0.05)。经过多因素分析后,aVR导联T波直立(OR:6.710,95%CI:1.713-26.282,p0.05)是住院期间严重心血管事件发生的独立危险因素。 结论: 1、行急诊PCI术的急性前壁心肌梗死患者中,入院心电图aVR导联T波直立者左室射血分数更低、非死亡患者住院时间更长。 2、行急诊PCI术的急性前壁心肌梗死患者中,入院心电图aVR导联T波直立者冠状动脉多支病变、住院期间严重心血管事件的发生率更高,,T波直立是患者住院期间严重心血管事件的独立危险因素。 3、入院心电图aVR导联T波直立对行急诊PCI术的急性前壁心肌梗死患者住院期间转归的预测评估具有一定临床价值。
[Abstract]:Objective: to investigate the relationship between the orientation of aVR lead T wave and the outcome during hospitalization in patients with acute anterior myocardial infarction (AMI) treated with emergency PCI. Methods: 75 patients with acute anterior myocardial infarction (mean age 59.5 卤11.6 years, male 59) who underwent emergency PCI from January 2011 to December 2012 were randomly selected for retrospective analysis. Standard 1: 1 symptom occurred within 12 hours (typical chest pain duration 30 minutes, including no effect of nitroglycerin) performed emergency PCI; 2electrocardiogram (ECG) characteristics or dynamic changes of St segment in acute anterior wall myocardial infarction (AMI) were measured to be 60 Ms after J point, and at least 2 ST segments of continuous electrocardiogram were more than 2 mm ~ (-3). The dynamic evolution of serum troponin I (cTnI) was found in patients with acute anterior wall myocardial infarction. No indication of angioplasty and coronary bypass graft history of severe valvular disease, ventricular hypertrophy, myocardial infarction in other parts of the ventricle, severe electrolyte disturbance, left or right bundle branch block, ventricular block, Pacing rhythm, preexcitation syndrome, atrial flutter, atrial fibrillation caused by ST segment can not be accurately measured. The patients were divided into T wave upright group (鈮

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