益髓补肾方对恶性血液病患者围化疗期生活质量的影响

发布时间：2018-09-14 15:35

【摘要】：目的:观察益髓补肾方对恶性血液病患者围化疗期生活质量的影响。方法:选取100例恶性血液病患者作为研究对象,按照随机数字法分为益髓补肾方组及对照组,各50例,益髓补肾方组在围化疗期给予益髓补肾方+化疗治疗,对照组在围化疗期给予单纯化疗,在一疗程的化疗结束后以问卷形式行生活质量的评估,共计4个疗程。结果:益髓补肾方组患者总有效率均优于对照组(44.00%/30.00%),不良反应的发生率低于对照组(30.00%/60.00%),差异均有统计学意义(P0.05);治疗后,益髓补肾方组患者总体健康状况、功能量表各项评分均高于对照组(P0.05);症状量表各项目评分均低于对照组(P0.05);六个单项测量项目除经济困难外,益髓补肾方组各指标评分均低于对照组(P0.05)。结论:益髓补肾方联合化疗治疗HM患者效果显著,可有效提高其治疗后的生活质量,值得借鉴和推广。
[Abstract]:Objective: to observe the effect of Yiwei Bushen recipe on the quality of life of patients with malignant hematopathy. Methods: 100 patients with malignant hematological diseases were randomly divided into two groups: the group of tonifying kidney and the group of tonifying kidney, 50 cases in each group. The group of tonifying kidney and tonifying kidney was treated with Yishui Bushen recipe in the peri-chemotherapy period. The control group was given simple chemotherapy during the peri-chemotherapy period and the quality of life (QOL) was evaluated by questionnaire after one course of chemotherapy for a total of 4 courses. Results: the total effective rate of Yishui Bushen prescription group was better than that of control group (44.00 / 30.00%), and the incidence of adverse reaction was lower than that of control group (30.00-60.00%), the difference was statistically significant (P0.05). The scores of each item of the function scale were higher than that of the control group (P0.05); the scores of each item of symptom scale were lower than that of the control group (P0.05); except economic difficulties, the scores of each index of Yiwei Bushen prescription group were lower than those of the control group (P0.05). Conclusion: Yiwei Bushen recipe combined with chemotherapy is effective in the treatment of HM patients, and can effectively improve the quality of life after treatment, which is worthy of reference and popularization.
【作者单位】：河北省中医院;
【基金】：河北省中医药管理局项目(2017033)
【分类号】：R733

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