糖尿病与非糖尿病青年心肌梗死的临床分析

发布时间：2018-09-14 20:09

【摘要】：目的探讨糖尿病与非糖尿病青年心肌梗死的不同之处。方法收集94例青年心肌梗死患者,分为糖尿病(DM)组和非糖尿病(。NDM)组,分析两组临床特点、冠状动脉造影结果、高危因素及预后的区别。结果DM组无典型胸痛(25.0%vs 7.6%)、非ST段抬高型心肌梗死(50.0%vs9.1%)、室壁运动异常(78.6%vs 42.4%)、双支病变(35.7%vs 21.2)、三支病变发生率(39.3%vs3.1%)、死亡率(10.7%vs 1.5%)均高于NDM组(P0.05或P0.01);DM组冠状动脉病变支数、冠状动脉病变积分(Gensini积分)分别为(2.110±0.875)支、(52.61±10.47)分;NDM组分别为(1.140±0.677)支、(34.02±10.24)分,两组间比较差异均有统计学意义(P0.05)。经多元线性回归分析发现,HbA_1c、吸烟是Gensini积分的独立危险因素。结论糖尿病青年心肌梗死患者临床特点更复杂,冠状动脉病变更严重,预后更差;HbA_1c和吸烟与Gensini积分呈正相关。
[Abstract]:Objective to explore the difference between diabetes mellitus and non-diabetic young myocardial infarction. Methods 94 young patients with myocardial infarction were divided into two groups: diabetic (DM) group and non-diabetic group. The clinical characteristics, coronary angiography results, high risk factors and prognosis of the two groups were analyzed. Results in DM group, there were no typical chest pain (25.0%vs 7.6%), non-ST segment elevation myocardial infarction (50.0% vs 9.1%), abnormal ventricular wall motion (78.6%vs 42.4%), double vessel disease (35.7%vs 21.2), three vessel disease (39.3% vs 3.1%), and the mortality (10.7%vs 1.5%) was higher than that in NDM group (P0.05 or P0.01). The scores of coronary artery lesion (Gensini) were (2.110 卤0.875), (52.61 卤10.47), (1.140 卤0.677) and (34.02 卤10.24), respectively. There was significant difference between the two groups (P0.05). Multiple linear regression analysis showed that smoking was an independent risk factor for Gensini score. Conclusion the clinical features of young diabetic patients with myocardial infarction are more complicated, the coronary artery disease is more serious, the prognosis is worse and HbA1c and smoking are positively correlated with Gensini score.
【作者单位】：湖北医药学院附属人民医院心脏中心;大连医科大学附属二院内分泌科;
【分类号】：R542.22;R587.1

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