QT间期缩短与变异型心绞痛室性心律失常

发布时间：2018-09-15 19:01

【摘要】：目的:分析变异型心绞痛发作时QT间期缩短与室性心律失常之间的相关性。方法:纳入我院变异型心绞痛患者共86例,收集每例患者24h动态心电图资料、变异型心绞痛发作时和不发作时的12导联心电图,计算发作时和不发作时的校正QT间期,与不发作时的校正QT间期对比,发作时的校正QT间期缩短的患者列入QT缩短组,其余患者列入对照组,并随访1年,对比两组在年龄、性别、吸烟比例、高敏C反应蛋白水平、高血压比例、糖尿病比例、血脂紊乱比例、冠脉病变比例的差异,对比两组在室性期前收缩负荷、室性心动过速发生比例、晕厥或猝死发生比例的差异。结果:QT缩短组吸烟比例、高敏C反应蛋白水平高于对照组,室性期前收缩负荷、室性心动过速发生比例亦高于对照组,差异均有统计学意义(P0.05),年龄、性别、高血压比例、糖尿病比例、血脂紊乱比例、冠状动脉病变比例与对照组无统计学差异(P0.05),晕厥或猝死发生比例与对照组无统计学差异(P0.05)。QT缩短组有1例患者合并继发性短QT间期综合征,并发生猝死。结论:变异型心绞痛发作时QT间期缩短与患者室性心律失常的发生存在正相关。
[Abstract]:Objective: to analyze the relationship between the shortening of QT interval and ventricular arrhythmia in patients with variant angina pectoris. Methods: 86 patients with variant angina pectoris were included in our hospital. The data of 24 h ambulatory electrocardiogram (ECG) of each patient were collected, and the 12-lead electrocardiogram (ECG) of the patients with variant angina pectoris during and without attack were collected, and the corrected QT intervals at and without attack were calculated. The patients with shorter corrected QT interval were included in the QT shortening group and the other patients were included in the control group. The two groups were followed up for one year. The age, sex, smoking ratio and Gao Min C-reactive protein level were compared between the two groups. The ratio of hypertension, diabetes mellitus, dyslipidemia and coronary artery disease were compared between the two groups in the proportion of ventricular presystolic load, ventricular tachycardia, syncope or sudden death. Results the smoking ratio, Gao Min C-reactive protein level, ventricular presystolic load and incidence of ventricular tachycardia in the control group were significantly higher than those in the control group (P0.05), age, sex and hypertension. There was no significant difference in the proportion of diabetes mellitus, dyslipidemia and coronary artery disease between the control group and the control group (P0.05). There was no significant difference in the incidence of syncope or sudden death between the control group and the control group (P0.05) .QT shortening group had 1 patient with secondary short QT interval syndrome. Sudden death occurred. Conclusion: there is a positive correlation between the shortening of QT interval and the occurrence of ventricular arrhythmias in patients with variant angina pectoris.
【作者单位】：桂林医学院附属医院心内科;
【基金】：广西高校科研资助项目(No:KY2015LX251)
【分类号】：R541.7

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