高血压合并冠心病的危险因素及相关性
发布时间：2018-09-18 17:08
【摘要】：目的探讨高血压患者合并冠心病(CAD)的危险因素及相关性。方法纳入2015年8月至2016年12月安徽医科大学第一附属医院心内科收治的高血压病患者258例,根据冠状动脉造影结果分为高血压组(124例),高血压合并冠心病组(134例)。记录研究对象的一般资料、血小板参数、血脂水平、肾功能指标。比较两组患者各指标的差异,并分析这些指标与高血压患者并发冠心病的相关关系。结果(1)与高血压组患者相比,高血压合并冠心病组患者的年龄较大、吸烟者较多、血小板分布宽度、平均血小板体积(MPV)、肌酐、血尿酸的值较高,而HDL-C水平较低,差异均有统计学意义(P0.05)。(2)多因素Logistic回归分析显示:年龄、吸烟史、MPV、血尿酸及低水平的HDL-C是高血压患者合并冠心病的独立危险因素[OR=1.062,95%CI:1.032~1.093;OR=2.048,95%CI:1.078~3.893;OR=2.737,95%CI:1.193~6.278;OR=1.006,95%CI:1.001~1.010;OR=0.280,95%CI:0.115~0.681(均P0.05)]。(3)Pearson相关分析结果显示:MPV和血尿酸呈正相关(r=0.17,P0.05)。结论年龄、吸烟史、MPV、血尿酸和较低的HDL-C值是高血压患者并发冠心病的危险因素,应当积极检测并预防,以降低高血压合并冠心病的发病风险。
[Abstract]:Objective to investigate the risk factors and correlation of coronary heart disease (CAD) in patients with hypertension. Methods from August 2015 to December 2016, 258 patients with hypertension were enrolled in the Department of Cardiology, first affiliated Hospital of Anhui Medical University. According to the results of coronary angiography, 258 patients were divided into hypertension group (124 cases) and hypertension with coronary heart disease group (134 cases). The general data, platelet parameters, blood lipid level and renal function were recorded. To compare the differences between the two groups and to analyze the correlation between these indexes and coronary heart disease (CHD) in patients with hypertension. Results (1) compared with the hypertension group, the patients with hypertension complicated with coronary heart disease had older age, more smokers, wider platelet distribution, higher mean platelet volume (MPV), creatinine, higher serum uric acid and lower HDL-C level. 宸紓鍧囨湁缁熻瀛︽剰涔，
本文编号：2248570
[Abstract]:Objective to investigate the risk factors and correlation of coronary heart disease (CAD) in patients with hypertension. Methods from August 2015 to December 2016, 258 patients with hypertension were enrolled in the Department of Cardiology, first affiliated Hospital of Anhui Medical University. According to the results of coronary angiography, 258 patients were divided into hypertension group (124 cases) and hypertension with coronary heart disease group (134 cases). The general data, platelet parameters, blood lipid level and renal function were recorded. To compare the differences between the two groups and to analyze the correlation between these indexes and coronary heart disease (CHD) in patients with hypertension. Results (1) compared with the hypertension group, the patients with hypertension complicated with coronary heart disease had older age, more smokers, wider platelet distribution, higher mean platelet volume (MPV), creatinine, higher serum uric acid and lower HDL-C level. 宸紓鍧囨湁缁熻瀛︽剰涔，
本文编号：2248570
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