个性化治疗方案联合中医治疗干预对高血压患者免疫功能及血压的影响

发布时间：2018-10-24 16:17

【摘要】：目的:探究个性化治疗方案联合中医针灸配合丹参静脉滴注对高血压患者免疫功能及血压的影响。方法:选取2013年1月1日—2014年12月31日医院心内科住院患者共570例,按照最小不平衡指数法分为观察组和对照组。观察组与对照组在均按照常规降压进行药物安排的同时,观察组患者行个性化治疗方案联合中医针灸治疗配合静脉滴注丹参注射液,对照组仅静脉滴注5%葡萄糖。比较两组患者治疗后T细胞亚群、免疫球蛋白、CIC、CRP、PIP指标及血压值的变化情况。结果:观察组与对照组CD3、CD4、CD8、CD_4~+/CD_8~+指标的值差异具有统计学意义(t值分别为2.62,2.07,2.61,2.21,P值分别为0.01,0.04,0.01,0.03)。治疗后观察组和对照组IgM差异不具有统计学意义(t=1.83;P=0.07),IgG、IgA、总Ig指标治疗后观察组与对照组差异具有统计学意义(t值分别为2.71,2.65,2.44;P0.05)。治疗前实验组与对照组收缩压、舒张压、血压控制率均无差异(P0.05),治疗后实验组收缩压、舒张压低于对照组(P0.05),血压控制率实验组高于对照组(P0.05)。结论:个性化治疗方案联合中医针灸配合丹参静脉滴注的干预疗法可以进一步改善患者体液以及细胞免疫功能,提高患者血压控制率。
[Abstract]:Objective: to explore the effect of individualized therapy combined with acupuncture and moxibustion combined with salvia miltiorrhiza intravenous drip on immune function and blood pressure in patients with hypertension. Methods: a total of 570 patients in the Department of Cardiology from January 1, 2013 to December 31, 2014 were selected and divided into observation group and control group according to the minimum imbalance index method. Patients in the observation group and control group were treated with individualized treatment combined with acupuncture and moxibustion of traditional Chinese medicine combined with intravenous infusion of salvia miltiorrhiza injection, while the patients in the control group received only 5% glucose intravenously. The changes of T cell subsets, immunoglobulin, CIC,CRP,PIP and blood pressure were compared between the two groups. Results: the difference of CD3,CD4,CD8,CD_4~ / CD_8~ between the observation group and the control group was statistically significant (t = 2.62 卤2.07 ~ 2.61 ~ 2.21) P = 0.01 ~ 0.04 ~ 0.01 ~ 0.03). There was no significant difference in IgM between the observation group and the control group after treatment (t = 1.83), but there was a significant difference between the observation group and the control group after the treatment of total IgG,IgA, Ig (t = 2.71 卤2.65, P 0.05). There was no difference in systolic blood pressure, diastolic blood pressure and blood pressure control rate between experimental group and control group before treatment (P0.05). After treatment, systolic blood pressure and diastolic blood pressure in experimental group were lower than those in control group (P0.05), and blood pressure control rate in experimental group was higher than that in control group (P0.05). Conclusion: the individualized therapy combined with acupuncture and moxibustion combined with salvia miltiorrhiza intravenous drip can further improve the humoral and cellular immune function of the patients and improve the blood pressure control rate of the patients.
【作者单位】：枣矿集团中心医院心内科;枣矿集团甘霖矿医院;
【基金】：青岛市中医科研计划项目(2014-zyz002)
【分类号】：R544.1

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