不同破口大小对B型主动脉夹层假腔内压力的影响

发布时间：2018-10-30 19:50

【摘要】：为了研究夹层内的血流动力学变化对夹层转归的重要影响,并期望为临床判断主动脉夹层发展及转归提供理论依据,通过3D打印技术制作不同出入口比例及破口大小的B型主动脉夹层模型,对主动脉夹层内血流变化进行模拟,并测量观察主动脉夹层模型假腔内压力变化及流场情况.真腔内固定压力为18.620、21.280 k Pa两组中,不同破口比例的假腔入口压力比普遍均小于夹层模型内其他假腔位置,且压力值低于真腔压力;真腔内压力为23.940 k Pa组中,破口比例为2∶1的夹层模型内假腔压力比较其他破口比例模型的压力比明显升高;所有模型真腔固定水压为21.280、23.940 k Pa下均可观测到同真腔压力下,真腔流速更快,其内部压力低于假腔.同一模型中,假腔压力普遍低于真腔压力;相同压力下,原发破口大的模型假腔流速相对较低,而涡流明显;相同模型相同压力下,假腔流速低于真腔,假腔的涡流更为明显,复杂的涡流和旋动对壁面造成冲击进而使假腔破裂风险增加.
[Abstract]:In order to study the important influence of hemodynamic changes in dissection on the outcome of dissection, and to provide a theoretical basis for clinical judgment of the development and outcome of aortic dissection. The B type aortic dissection model with different entrance and exit ratio and size was made by 3D printing technique. The blood flow in aortic dissection was simulated and the pressure change and flow field in pseudo-lumen of aortic dissection model were measured and observed. In the two groups with a true cavity pressure of 18.620 ~ 21.280 k / Pa, the inlet pressure ratio of different fracturing ratio was generally smaller than that of other pseudo-cavity positions in the sandwich model, and the pressure value was lower than that of the true cavity pressure. In the group of true cavity pressure of 23.940 k Pa, the pressure ratio of false cavity in the sandwich model with a break ratio of 2:1 was significantly higher than that of the other models. It is observed that the velocity of true cavity is faster and the internal pressure is lower than that of pseudo-cavity under the same true cavity pressure at a fixed water pressure of 21.280 ~ 23.940k Pa. In the same model, the pressure of false cavity is generally lower than that of true cavity, and the velocity of false cavity with large primary break is relatively low and the eddy current is obvious under the same pressure. Under the same model and same pressure, the velocity of false cavity is lower than that of true cavity, and the eddy current of false cavity is more obvious.
【作者单位】：北京工业大学生命科学与生物工程学院;首都医科大学附属北京安贞医院;首都儿科研究所;
【分类号】：R318.01

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