盐酸甲氧氯普胺注射液预防ST段抬高型心肌梗死急诊PCI术中及术后呕吐的疗效

发布时间：2018-11-04 14:43

【摘要】：目的:观察应用盐酸甲氧氯普胺注射液预防ST段抬高型心肌梗死(STEMI)患者急诊经皮冠状动脉介入治疗(PCI)术中及术后呕吐的疗效。方法:选择2014年1月至2016年4月进入我院的急诊STEMI,并需要进行PCI治疗的患者132例,随机分为观察组和对照组。观察组患者PCI术前即给予盐酸甲氧氯普胺注射液做呕吐的预防治疗;对照组不给予预防治疗,如出现症状再给予相应的对症治疗。观察术中及术后24 h内呕吐的例数、频次、持续时间及其严重程度。结果:观察组术中和术后24 h内发生呕吐的患者数、呕吐的发生率及呕吐持续的时间均显著的低于对照组,观察组术后24 h内的呕吐严重程度评分显著的低于对照组,差异均具有统计学意义,P0.05。结论:SEMI急诊PCI术前预防性应用盐酸甲氧氯普胺注射液,可显著的减少患者术中及术后呕吐的发生。
[Abstract]:Objective: to observe the effect of metoclopramide hydrochloride injection on the prevention of vomiting during and after ST segment elevation myocardial infarction (STEMI) by percutaneous coronary intervention (PCI). Methods: from January 2014 to April 2016, 132 patients with emergency STEMI, who were admitted to our hospital and needed to be treated with PCI were randomly divided into two groups: the observation group and the control group. The patients in the observation group were given metoclopramide hydrochloride injection to prevent vomiting immediately before PCI, while the control group was not given preventive treatment, and the corresponding symptomatic treatment was given if symptoms appeared. The number, frequency, duration and severity of vomiting during operation and 24 hours after operation were observed. Results: the number of patients with vomiting during operation and 24 hours after operation, the incidence of vomiting and the duration of vomiting in the observation group were significantly lower than those in the control group, and the scores of the severity of vomiting in the observation group were significantly lower than those in the control group within 24 hours after operation. The difference was statistically significant (P 0.05). Conclusion: the prophylactic use of metoclopramide hydrochloride injection before SEMI emergency PCI can significantly reduce the incidence of vomiting during and after operation.
【作者单位】：贵州省人民医院心内科;
【基金】：贵州省科技计划项目(编号:黔科合LH字【2015】7158号)
【分类号】：R542.22

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