心脏骤停后综合征的相关研究进展
发布时间：2018-11-26 12:35
【摘要】：心脏骤停后综合征(post-cardiac arrest syndrome,PCAS),过去称为“复苏后综合征”,是临床上的急危重症。它是心脏骤停(CA)患者经过心肺复苏恢复自主循环后(resumption of spontaneous circulation,ROSC)所产生的急性缺血-再灌注损伤及一系列复杂的病理生理改变。若不及时救治,临床病死率很高。造成这种低存活率的原因极其复杂,为了提高存活率,需及早治疗,目前临床上的治疗措施主要有心电血氧重症监护、早期血流动力学优化、氧合与机械通气、亚低温治疗等,其中亚低温治疗是目前唯一证实对脑保护有效的措施,是当前研究热点,但仍存在不少争议。因PCAS的高死亡率和神经功能致残率,临床上需通过某些相关因素及评分方法对PCAS患者的预后做出判断评估以便指导临床工作中的诊治,同时减少不必要的治疗为患者家庭所带来的巨大的负担。本文通过文献回顾,就心脏骤停后综合征的临床治疗进展及预后相关因素做一综述。
[Abstract]:Cardiac arrest syndrome (post-cardiac arrest syndrome,PCAS), formerly known as postresuscitation syndrome, is a clinical emergency. It is an acute ischemia-reperfusion injury and a series of complex pathophysiological changes in (CA) patients after cardiopulmonary resuscitation (CPR) and spontaneous circulation (resumption of spontaneous circulation,ROSC). If not timely treatment, the clinical mortality is very high. The reasons for this low survival rate are extremely complicated. In order to improve the survival rate, early treatment is required. At present, the main clinical treatment measures are ECG intensive care, early hemodynamics optimization, oxygenation and mechanical ventilation, mild hypothermia treatment, etc. Mild hypothermia therapy is the only effective measure to protect the brain. Because of the high mortality rate and neurological disability rate of PCAS, it is necessary to evaluate the prognosis of PCAS patients by some relevant factors and scoring methods in order to guide the diagnosis and treatment in clinical work. At the same time, reduce the unnecessary treatment on the patient's family to bring a huge burden. This article reviews the clinical treatment and prognostic factors of post-cardiac arrest syndrome.
【学位授予单位】：蚌埠医学院
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R541.78
本文编号：2358575
[Abstract]:Cardiac arrest syndrome (post-cardiac arrest syndrome,PCAS), formerly known as postresuscitation syndrome, is a clinical emergency. It is an acute ischemia-reperfusion injury and a series of complex pathophysiological changes in (CA) patients after cardiopulmonary resuscitation (CPR) and spontaneous circulation (resumption of spontaneous circulation,ROSC). If not timely treatment, the clinical mortality is very high. The reasons for this low survival rate are extremely complicated. In order to improve the survival rate, early treatment is required. At present, the main clinical treatment measures are ECG intensive care, early hemodynamics optimization, oxygenation and mechanical ventilation, mild hypothermia treatment, etc. Mild hypothermia therapy is the only effective measure to protect the brain. Because of the high mortality rate and neurological disability rate of PCAS, it is necessary to evaluate the prognosis of PCAS patients by some relevant factors and scoring methods in order to guide the diagnosis and treatment in clinical work. At the same time, reduce the unnecessary treatment on the patient's family to bring a huge burden. This article reviews the clinical treatment and prognostic factors of post-cardiac arrest syndrome.
【学位授予单位】：蚌埠医学院
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R541.78
【参考文献】
相关期刊论文 前1条
1 刘延媛;;心肺复苏后患者亚低温治疗对肺功能的影响[J];实用心脑肺血管病杂志;2010年03期
，本文编号：2358575
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