分级运动康复对老年慢性心力衰竭患者心功能及生活质量的影响

发布时间：2019-01-02 20:24

【摘要】：目的探讨根据心功能的不同分级对老年慢性心力衰竭(CHF)患者进行运动康复(ET)后患者心功能及生活质量的变化。方法选取老年CHF患者72例,随机分为对照组(n=37)和ET组(n=35)。对照组给予指南指导下的药物治疗,ET组在药物治疗的基础上联合运动训练。观察两组治疗前及治疗后3、6、12个月的纽约心脏病协会(NYHA)心功能分级、6 min步行距离(6MWD)、左心室射血分数(LVEF)、血浆B型钠尿肽(BNP)、明尼苏达心功能不全生命质量量表(MLHFQ)指标的变化。同时观察12个月后严重不良事件及副作用发生情况。结果对照组失访2例,70例患者完成随访,随访时间为12个月。12个月后ET组较对照组NYHA分级明显改善(P=0.001),6MWD明显上升(P=0.006),LVEF明显上升(P=0.005),BNP明显下降(P=0.001),MLHFQ明显下降(P=0.004)。12个月后ET组较对照组严重不良事件及副作用发生例数并未增加(P=0.329)。结论药物治疗联合ET可以改善老年CHF患者的心功能及生活质量,进行ET是安全可行的。
[Abstract]:Objective to investigate the changes of cardiac function and quality of life in elderly patients with chronic heart failure (CHF) after (ET) after exercise rehabilitation according to different grades of cardiac function. Methods 72 elderly patients with CHF were randomly divided into control group (n = 37) and ET group (n = 35). The control group was given drug therapy under the guidance of the guidelines, while the ET group combined exercise training on the basis of drug therapy. The (NYHA) cardiac function grading, 6 min walking distance (6MWD), left ventricular ejection fraction (LVEF),) and plasma type B natriuretic peptide (BNP), (BNP),) were observed before treatment and 3 months and 12 months after treatment in the two groups. Changes of (MLHFQ) parameters in Minnesota Cardiac insufficiency quality of Life scale. At the same time, serious adverse events and side effects were observed after 12 months. Results in the control group, 2 cases lost the visit and 70 cases were followed up for 12 months. After 12 months, the NYHA grading and 6MWD in the ET group were significantly improved than those in the control group (P0. 001) and 6MWD was significantly increased (P0. 005). BNP decreased significantly (P0. 001), MLHFQ decreased (P0. 004). After 12 months, the number of serious adverse events and side effects in ET group was not increased compared with control group (P0. 329). Conclusion Drug therapy combined with ET can improve cardiac function and quality of life in elderly patients with CHF. ET is safe and feasible.
【作者单位】：云南省第三人民医院老年病科;
【基金】：云南省卫生厅高层次卫生技术人才培养专项经费资助(D-201208)
【分类号】：R541.6

【相似文献】