巨噬细胞胆固醇转运相关蛋白研究进展
发布时间：2019-01-21 08:12
【摘要】：动脉粥样斑块中泡沫细胞的形成与巨噬细胞胆固醇的转运密切相关,巨噬细胞胆固醇转运是胆固醇逆转运中的一个重要过程,它可清除外周组织过多的胆固醇,对维持细胞内胆固醇稳定、延缓动脉粥样硬化的发生发展有着重要意义.这个过程涉及到许多转运相关蛋白的作用,如三磷酸腺苷结合盒转运体A1/G1、载脂蛋白A-Ⅰ、胆固醇脂转运蛋白、卵磷脂胆固醇酰基转移酶等.本文就巨噬细胞胆固醇转运过程中相关蛋白的作用做一综述,以期为动脉粥样硬化相关疾病的防治研究提供新的思路.
[Abstract]:The formation of foam cells in atherosclerotic plaques is closely related to the transport of cholesterol in macrophages. Cholesterol transport in macrophages is an important process in reversing cholesterol transport. It is of great significance to maintain the stability of intracellular cholesterol and delay the occurrence and development of atherosclerosis. This process involves the roles of many transporter proteins, such as adenosine triphosphate binding cassette transporter A1 / G1, apolipoprotein A- 鈪，
本文编号：2412468
[Abstract]:The formation of foam cells in atherosclerotic plaques is closely related to the transport of cholesterol in macrophages. Cholesterol transport in macrophages is an important process in reversing cholesterol transport. It is of great significance to maintain the stability of intracellular cholesterol and delay the occurrence and development of atherosclerosis. This process involves the roles of many transporter proteins, such as adenosine triphosphate binding cassette transporter A1 / G1, apolipoprotein A- 鈪，
本文编号：2412468
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