原发性高血压病人超敏C反应蛋白与血压及血管内皮功能关系的研究
发布时间：2019-02-26 12:49
【摘要】：目的探讨原发性高血压病人血压、血管内皮功能与超敏C反应蛋白(high-sensitive C-reactive protein,hs-CRP)的关系。方法入选111例未经治疗的轻度原发性高血压病病人,并根据hs-CRP的数值将高血压病人分为2组:高hs-CRP组(hs-CRP2.78)42例和低hs-CRP组(hs-CRP≤2.78)69例。所有受试者均行Endo-PAT2000无创内皮功能检测仪检测反应性充血指数(reactive hyperemia index,RHI),并检测hs-CRP,测量收缩压及舒张压。结果高hs-CRP组收缩压及脉压明显高于低hs-CRP组;Pearson相关分析结果表明,hs-CRP与收缩压(r=-0.247,P=0.010)呈负相关。结论炎性反应因子可能与原发性高血压病人血管内皮损伤有关,但仍需要进一步纵向研究来更好的阐明内皮功能与炎性反应因子之间的因果关系。
[Abstract]:Objective to investigate the relationship between blood pressure, vascular endothelial function and hypersensitive C-reactive protein (high-sensitive C-reactive protein,hs-CRP) in patients with essential hypertension (EH). Methods one hundred and eleven untreated patients with mild essential hypertension were divided into two groups according to the value of hs-CRP: 42 patients with high hs-CRP (hs-CRP2.78) and 69 patients with low hs-CRP (hs-CRP 鈮，
本文编号：2430785
[Abstract]:Objective to investigate the relationship between blood pressure, vascular endothelial function and hypersensitive C-reactive protein (high-sensitive C-reactive protein,hs-CRP) in patients with essential hypertension (EH). Methods one hundred and eleven untreated patients with mild essential hypertension were divided into two groups according to the value of hs-CRP: 42 patients with high hs-CRP (hs-CRP2.78) and 69 patients with low hs-CRP (hs-CRP 鈮，
本文编号：2430785
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