饮酒对高血压患者OSAS睡眠参数及睡眠结构影响的相关研究

发布时间：2019-03-17 19:42

【摘要】：目的分析饮酒对OSAS患者睡眠结果及睡眠结构的影响。方法对260例2015年8月至2016年9月就诊于新疆维吾尔自治区高血压中心的高血压患者,采用回顾性问卷调查所有研究对象的饮酒史,根据饮酒分组标准,最后我们把入选人群分为少量饮酒组病人(91)、大量饮酒组病人(79)、非饮酒组病人(93)。以AHI及LSaO2严重程度分组比较OSAS患者睡眠参数及睡眠结构的变化。结果1.对260例病人根据饮酒程度比较发现:非饮酒的病人、少量饮酒的病人及大量饮酒的病人的生化资料、AHI、LSa O2以及睡眠结构差别均无统计学意义(P0.05)。2.进一步以AHI严重程度分组:AHI≥15病人中,非饮酒的病人、少量饮酒的病人及大量饮酒的病人的AHI、LSaO2以及睡眠结构没有差别(P0.05);AHI15病人中,非饮酒的病人、少量饮酒的病人及大量饮酒的病人的AHI、LSaO2、睡眠2期存在差异(P0.05)。3.以LSa O2严重程度分组:LSaO280%病人中,非饮酒的病人、少量饮酒的病人及大量饮酒的病人的AHI、LSaO2未见差异(P0.05),但三组病人的睡眠2期存在差异(P0.05);LSa O2≥80%病人中,非饮酒组病人、少量饮酒组病人与大量饮酒组病人的LSaO2存在差异(P0.05),三组病人的AHI无统计学意义,并且发现三组病人的睡眠2期、睡眠3期、睡眠4期之间存在统计学差异(P0.05)。结论饮酒对AHI15及LSaO2≥80%的病人的AHI、LSaO2以及睡眠结构影响更加显著,而对AHI≥15及LSaO280%的病人的AHI、LSaO2以及睡眠结构影响无明显差异。可能受患者的年龄及肥胖程度的影响掩盖了酒精的作用,因为发现在AHI15次/分及LSaO280%分组中,年龄及BMI都具有统计学差异。而众多的研究表明,肥胖和年龄也是导致OSAS加重的重要因素。
[Abstract]:Objective to analyze the effects of alcohol drinking on sleep outcome and sleep structure in OSAS patients. Methods 260 patients with hypertension from August 2015 to September 2016 in Xinjiang Uygur Autonomous region were investigated with a retrospective questionnaire. Finally, we divided the selected population into a small drinking group (91), a heavy drinking group (79), and a non-drinking group (93). The changes of sleep parameters and sleep structure in OSAS patients were compared by AHI and LSaO2 severity groups. Outcome 1. The results showed that there was no significant difference in biochemical data, AHI,LSa O2 and sleep structure between non alcohol drinker, small alcohol drinker and heavy alcohol drinker according to the degree of drinking (P0.05). According to the severity of AHI, there was no significant difference in AHI,LSaO2 and sleep structure among patients with AHI 鈮，

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