不同类型高血压患者脉压、脉压指数与肱踝动脉脉搏波传导速度和踝臂血压指数的关系

发布时间：2019-05-27 13:16

【摘要】：目的观察不同类型高血压患者脉压、脉压指数与肱踝动脉脉搏波传导速度(baPWV)和踝臂血压指数(ABI)的相关性。方法入选2015年1月至2017年3月初诊为原发性高血压的患者260例为观察组,同期行体检的健康人群220人为对照组。计算和比较对照组与观察组[不同高血压类型:单纯收缩期高血压组(ISH)、单纯舒张期高血压组(IDH)、收缩期舒张期高血压组(SDH);不同脉压:脉压(收缩压-舒张压,mm Hg)≤50组、51~60组、60组;不同脉压指数(脉压/收缩压):0.4组、0.4~0.5组、0.5组]baPWV和ABI水平的差异。结果观察组患者的收缩压、舒张压、脉压和脉压指数高于对照组,baPWV水平高于而ABI水平低于对照组(均P0.05)。高血压类型中,ISH组baPWV水平最高而ABI水平最低,SDH组与IDH组和对照组baPWV、ABI比较差异有统计学意义(均P0.05),IDH组和对照组baPWV、ABI比较差异无统计学意义(P0.05)。不同脉压和脉压指数亚组的baPWV水平与ABI水平存在差异,脉压和脉压指数越大者,baPWV越高而ABI水平越低(均P0.05)。Pearson线性相关分析显示,baPWV与ABI呈负相关(r=-0.784,P0.05);调整年龄、BMI、血脂等影响因素后,行偏相关分析,两者仍呈负相关(r=-0.766,P0.05)。以baPWV或ABI为因变量,年龄、血脂、血压、血糖和BMI为自变量进行多元线性逐步回归分析显示,脉压(β=0.323或β=-0.407)和脉压指数(β=0.352或β=-0.420)是baPWV增加或ABI减少的影响因素(均P0.05)。结论不同类型高血压患者baPWV和ABI水平存在差异,ISH组baPWV水平最高而ABI水平最低,脉压和脉压指数越大者baPWV越高而ABI水平越低。
[Abstract]:Objective to observe the correlation between pulse pressure, pulse pressure index and brachial artery pulse wave conduction velocity (baPWV) and ankle brachial blood pressure index (ABI) in patients with different types of hypertension. Methods 260 patients with essential hypertension from January 2015 to March 2017 were selected as observation group, and 220 healthy people who underwent physical examination at the same time were selected as control group. Calculation and comparison of control group and observation group [different types of hypertension: simple systolic hypertension group (ISH), simple diastolic hypertension group (IDH), systolic diastolic hypertension group (SDH); Different pulse pressure: pulse pressure (systolic blood pressure-diastolic blood pressure, mm Hg) 鈮，

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