基于时间射血分数评估心功能的设想

发布时间：2019-06-27 19:48

【摘要】：射血分数(ejection fraction,EF)是每搏输出量与心室舒张末容积的百分比,由于没有时间限制,不能反映心脏射血的敏捷性与时效性,为泵血功能的总体反映。在目前射血分数保留的心衰(heart failure with preserved EF,HFp EF)患者日益增多的条件下,EF临床意义有限。而泵血是心脏最基本的功能,在EF无法评估心功能的条件下,如何用其他相对客观且简单指标进行心功能评估于临床显得尤为重要。虽已有较多相关研究,但结果均不理想。而心电图QRS波时限与心肌收缩时间有较好的相关性,满足时间射血分数(timed EF,TEF)中时间因素的要求,符合用TEF代替传统的EF的设想,即以EF与心电图QRS波时限比值评估心功能。它既包含心脏原有的EF,又加入特定的时间限制,能较全面而客观地反映心脏实际泵血能力,特别是对HFp EF患者和心衰早期患者心功能的评估,是心脏泵血功能评估新指标的有益尝试和探讨。
[Abstract]:Ejection fraction (ejection fraction,EF) is the percentage of stroke volume and ventricular end-diastolic volume. Because there is no time limit, it can not reflect the agility and timeliness of cardiac ejection, and it is the overall reflection of pumping function. Under the increasing number of patients with heart failure (heart failure with preserved EF,HFp EF with ejection fraction retention, the clinical significance of EF is limited. Blood pumping is the most basic function of the heart. Under the condition that EF can not evaluate the cardiac function, how to evaluate the cardiac function with other relatively objective and simple indexes is particularly important in clinic. Although there have been many related studies, the results are not ideal. However, there is a good correlation between the duration of QRS wave and the time of myocardial contraction, which meets the requirements of time factor in time ejection fraction (timed EF,TEF) and accords with the assumption of using TEF instead of traditional EF, that is, the ratio of EF to QRS wave duration of electrocardiogram is used to evaluate cardiac function. It not only contains the original EF, of the heart, but also adds a specific time limit, which can comprehensively and objectively reflect the actual pumping ability of the heart, especially the evaluation of cardiac function in patients with HFp EF and early patients with heart failure. It is a useful attempt and discussion for the evaluation of new indexes of cardiac pumping function.
【作者单位】：陕西省咸阳市第一人民医院;
【分类号】：R541

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