冠心病患者baPWV与颈动脉IMT相关性分析及其中医体质分布
发布时间:2019-06-30 21:16
【摘要】:目的:初步探讨冠状动脉粥样硬化性心脏病(以下简称“冠心病”)患者肱踝脉搏波传导速度(ba PWV)和颈动脉内中膜厚度(IMT)的相关性,及患者中医体质分布情况。材料与方法:选择2015年5月-2017年1月辽宁中医药大学附属医院心内一科收治的117例冠心病患者为研究对象,平均年龄58.79±9.39(40-80)岁,其中男44例,女73例,采用日本VS-1000动脉硬化诊断仪进行检测,根据ba PWV检测结果,分为对照组(ba PWV1400cm/s)56例,观察组(ba PWV≥1400 cm/s)61例,记录患者的详细病史,采集患者的身高、体重、血脂等信息,计算体重指数,测踝臂指数、颈动脉IMT,并对入选患者的中医体质进行问卷调查。所有数据用SPSS17.0统计分析软件进行处理、分析,假设检验统一使用双侧检验,以P0.05作为有统计学意义,以P0.01作为有显著性统计学意义。结果:1.两组患者危险因素的比较:在年龄、BMI、TG、CHOL、LDL-C和颈动脉IMT值这六项有明显差异,P0.05,差异有统计学意义。2.两组患者危险因素相关性的比较:年龄、BMI、TG、CHOL、LDL-C和IMT与ba PWV呈显著正相关,P0.05,差异有统计学意义。相关系数r:1rIMTrTGrBMIrCHOLr年龄r LDL-C0。3.建立、分析两组患者危险因素的回归模型:经逐步回归,最终进入模型的两个因素为TG和颈动脉IMT,P0.01,有显著统计学意义。logit(P)=-9.885+1.314×TG+0.687×IMT(χ2=24.483,P=0.000)4.经Fisher的精确检验,得出两组患者的中医体质分布状态:冠心病患者ba PWV不同,中医体质分布不同,差异有统计学意义(χ2=16.051,P=0.019)。具体如下:对照组的患者体质为:气虚质痰湿质=血瘀质气郁质=湿热质阳虚质=平和质阴虚质特禀质;观察组患者为:痰湿质血瘀质气虚质=气郁质湿热质阳虚质阴虚质平和质特禀质。结论:1.ba PWV与颈动脉IMT显著正相关,颈动脉内膜增厚的冠心病患者,其IMT每增厚0.1mm可能导致ba PWV加快的危险性增加1.988倍。2.ba PWV加快的冠心病患者以痰湿质为主要中医体质,其次为血瘀质、气虚质、气郁质。3.通过易感体质识别潜在的冠心病患者,有助于早期发现冠心病亚临床状态人群,并通过改善患者体质防治动脉粥样硬化。
[Abstract]:Objective: to investigate the correlation between brachial and malleolus pulse wave conduction velocity (ba PWV) and carotid intima-media thickness (IMT) in patients with coronary atherosclerotic heart disease (CAD), and the distribution of TCM physique in patients with coronary atherosclerotic heart disease (CAD). Materials and methods: 117 patients with coronary heart disease treated in the Department of Cardiology, affiliated Hospital of Liaoning University of traditional Chinese Medicine from May 2015 to January 2017 were selected as subjects with an average age of 58.79 卤9.39 (40 鈮,
本文编号:2508258
[Abstract]:Objective: to investigate the correlation between brachial and malleolus pulse wave conduction velocity (ba PWV) and carotid intima-media thickness (IMT) in patients with coronary atherosclerotic heart disease (CAD), and the distribution of TCM physique in patients with coronary atherosclerotic heart disease (CAD). Materials and methods: 117 patients with coronary heart disease treated in the Department of Cardiology, affiliated Hospital of Liaoning University of traditional Chinese Medicine from May 2015 to January 2017 were selected as subjects with an average age of 58.79 卤9.39 (40 鈮,
本文编号:2508258
本文链接:https://www.wllwen.com/yixuelunwen/xxg/2508258.html
最近更新
教材专著