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器质性心脏病在STEMI患者中的发生率及其临床关联性

发布时间:2021-03-20 08:33
  背景:心肌梗死(MI)是全世界内发病率和死亡率最高的疾病之一。心肌梗死通常是由于冠状动脉在斑块破裂或侵蚀的部位发生血栓导致血管闭塞所致。怀疑或确诊为急性心肌缺血或梗死的患者可诊断为急性冠脉综合征(ACS)。非ST段抬高型心肌梗死(NSTEMI),不稳定型心绞痛和ST段抬高型心肌梗死(STEMI)是ACS的三种类型。ST段抬高型心肌梗死(STEMI)是由心肌缺血的典型症状、持续性ST段抬高的心电图改变(STE)以及其后继发的心肌损伤标志物水平改变三者共同定义的临床综合征。在标准条件下进行诊断时,STEMI的诊断标准为心电图表现为至少有两个相邻导联ST段抬高≥1mm(0.1mV)以及心肌损伤标志物升高。心电图(ECG)是针对心肌梗死患者的初步检查,心肌损伤标志物的血液检查可以证明患者患有心肌梗死。而超声心动图检查(ECHO)由于可以进一步诊断心肌梗死的早期和晚期并发症,从而被认为是对于所有急性心肌梗死患者而言具有诊断意义的诊断性检查项目。超声心动图检查是一种非侵入性的诊断技术,它可以提供有关心脏功能和血液动力学的信息并且对患有AMI机械并发症的患者进行病情评估。AMI的主要机械并发症分别是... 

【文章来源】:吉林大学吉林省 211工程院校 985工程院校 教育部直属院校

【文章页数】:87 页

【学位级别】:硕士

【文章目录】:
摘要
abstract
CHAPTER 1:INTRODUCTION
    1.1 BACKGROUND
    1.2 UNIVERSAL DEFINITION OF MYOCARDIAL INJURY AND MYOCARDIAL INFARCTION
    1.3 EPIDEMIOLOGY
    1.4 CLASSIFICATION
    1.5 RISK FACTORS
    1.6 PATHOGENESIS
    1.7 CLINICAL FEATURES
    1.8 INVESTIGATION
        1.8.1 Electrocardiography
        1.8.2 Cardiac Enzymes and Cardiac Markers
        1.8.3 Chest X-ray
        1.8.4 Echocardiography
        1.8.5 Coronary Angiography
    1.9 PROGNOSIS
    1.10 TREATMENT
        1.10.1 Prehospital care
        1.10.2 Emergency department and in-hospital management
        1.10.3 Routine measures in the treatment of STEMI
        1.10.4 Treatment in right ventricular infarction
    1.11 COMPLICATIONS
CHAPTER 2:LITERATURE REVIEW
    2.1 STRUCTURAL HEART DISEASE AS A COMPLICATION OF MYOCARDIAL INFARCTION
        2.1.1 Background
        2.1.2 Structural heart disease
    2.2 MECHANICAL COMPLICATION OF STEMI
        2.2.1 Mitral regurgitation(MR):
        2.2.2 Tricuspid regurgitation(TR)
    2.3 AORTIC REGURGITATION
CHAPTER 3:METHODS AND MATERIALS
    3.1 OBJECTIVE OF STUDY
        3.1.1 Aim
        3.1.2 Objective
    3.2 STUDY DESIGN
    3.3 STUDY POPULATION
    3.4 METHOD
        3.4.1 Inclusion criteria
        3.4.2 Exclusion criteria
        3.4.3 Electrocardiography
        3.4.4 Echocardiography
        3.4.5 Division of patients
    3.5 STATISTICAL ANALYSIS
    3.6 STUDY LIMITATIONS
CHAPTER 4:RESULTS
    4.1 STUDY POPULATION
    4.2 BIOCHEMICAL PARAMETERS AND ECHOCARDIOGRAPHIC MEASUREMENT
    4.3 COMPARISON BETWEEN STRUCTURAL HEART DISEASE AND NON-STRUCTURAL HEART DISEASE
    4.4 COMPARISON BETWEEN PATIENTS WITH MITRAL REGURGITATION AND WITHOUT MITRAL REGURGITATION
    4.5 COMPARISON BETWEEN THE PATIENT WITH AORTIC REGURGITATION AND WITHOUT AORTIC REGURGITATION
    4.6 COMPARISON BETWEEN THE PATIENT WITH TRICUSPID REGURGITATION AND WITHOUT TRICUSPID REGURGITATION
    4.7 MAJOR ADVERSE CARDIOVASCULAR EVENTS(MACE)
CHAPTER 5:DISCUSSION
CHAPTER 6:CONCLUSION
REFERENCE
AUTHOR'S INTRODUCTION
ACKNOWLEDGEMENT



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