MRI对鼻咽癌放疗后改变的影像价值研究

发布时间：2018-03-18 10:05

本文选题：鼻咽癌　切入点：MRI　出处：《新疆医科大学》2010年硕士论文　论文类型：学位论文

【摘要】： 目的:探讨磁共振成像对鼻咽癌放射治疗后改变的影像诊断价值,尤其是放疗后复发的诊断及鉴别诊断。方法:收集新疆肿瘤医院2006年1月-2009年10月经病理证实的鼻咽癌病例67例,其中39例行弥散加权像(DWI)扫描。所有病例均行放射治疗、有完整MR复查资料,分析其放疗后不同情况下的MRI表现,及MRI对复发或残留的检出,并进一步利用弥散加权像测定的ADC值来研究放疗后复发与纤维化及残留的鉴别。结果:①MRI基本能反应放疗后咽壁不同变化情况;②MR最初对复发或残留的检出,敏感性85.00%,特异性91.49%,准确性89.55%;③放疗后鼻咽纤维化者ADC值较复发者及残留者明显高(P0.05),而复发者咽后淋巴结ADC值较纤维化者及残留者明显低(P0.05)。结论:MRI能清晰地显示鼻咽癌放疗后变化情况,并且对复发的检出准确性较高,放疗后纤维化、残留及复发者ADC值的不同或许为鉴别诊断提供一定参考价值,MRI对放射治疗鼻咽癌的效果评价至关重要。
[Abstract]:Objective: to evaluate the diagnostic value of magnetic resonance imaging (MRI) in patients with nasopharyngeal carcinoma (NPC) after radiotherapy. Methods: 67 cases of nasopharyngeal carcinoma (NPC) confirmed by pathology from January 2006 to 2009 in Xinjiang tumor Hospital were collected, 39 of them underwent DWI scan. All cases were treated with radiotherapy. There were complete Mr reexamination data, the MRI manifestations of the patients under different conditions after radiotherapy, and the detection of recurrence or residual by MRI. The differential diagnosis of recurrence and fibrosis and residual after radiotherapy was studied by using the ADC value measured by diffusion weighted imaging. Results the differential diagnosis of recurrence and residual in pharynx wall after radiotherapy was basically reflected by different changes in pharyngeal wall after radiotherapy. The sensitivity was 85.00 and the specificity was 91.49. The accuracy of ADC in patients with nasopharyngeal fibrosis after radiotherapy was significantly higher than that in patients with recurrent nasopharynx fibrosis and those with residual nasopharynx (P 0.05), while the ADC value of retropharyngeal lymph nodes in recurrent patients was significantly lower than that in patients with fibrosis and residual nasopharynx (P 0.05). Conclusion\% ADC can clearly show nasopharynx fibrosis. Changes in cancer after radiotherapy, The difference of ADC values of fibrosis, residual and recurrence after radiotherapy may provide a certain reference value for differential diagnosis. It is very important to evaluate the effect of radiotherapy on nasopharyngeal carcinoma.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R739.63

【参考文献】