窄带光谱成像技术联合放大内镜在咽喉部肿瘤诊断中的应用

发布时间：2018-08-04 10:50

【摘要】：目的探讨窄带光谱成像技术(narrow band imaging,NBI)联合放大内镜检查在咽喉部肿瘤诊断中的应用价值。方法选取2011年7月至2014年6月我科胃镜中心的105 000例患者进行胃镜检查,在胃镜检查前先常规用白光进行咽喉部的观察,然后再用NBI模式光对咽部进行观察,发现病变及时送病理检查。结果检出咽喉部肿瘤22例(0.021%),包括进展期鳞状细胞癌10例(0.010%)和早期癌(包括高级别上皮内瘤变及原位癌)12例(0.011%)。其中在进展期鳞状细胞癌的诊断中,NBI内镜(9例)和白光内镜(10例),两组无显著差异(P0.05);在早期癌的诊断中,NBI内镜(12例)和白光内镜(1例),两组有显著差异(P0.01)。咽部癌并食道癌者共占45.45%(10/22),咽部癌合并直肠癌1例。结论 NBI放大内镜检查前对咽喉部早期癌的检出率优于白光内镜,但是对于进展期咽喉癌的诊断,NBI内镜和白光内镜无差异。在检查中应特别注意咽部癌和食道癌同时存在的情况。
[Abstract]:Objective to evaluate the value of narrow band spectral imaging (narrow band) combined with magnifying endoscopy in the diagnosis of pharyngeal and laryngeal tumors. Methods from July 2011 to June 2014, 105,000 patients were examined by gastroscopy. The pharyngopharynx was observed with white light before gastroscopy, and then with NBI mode light. The pathological changes should be sent to pathological examination in time. Results 22 cases (0.021%) of pharyngeal and laryngeal neoplasms were detected, including 10 cases of advanced squamous cell carcinoma (0.010%) and 12 cases of early stage carcinoma (including high grade intraepithelial neoplasia and carcinoma in situ) (0.011%). There was no significant difference between NBI endoscopy (9 cases) and white light endoscopy (10 cases) in the diagnosis of advanced squamous cell carcinoma (P0.05), and there was significant difference between the two groups (P0.01) in early diagnosis of squamous cell carcinoma (12 cases) and white light endoscopy (1 case). There were 45.45% (10 / 22) cases of pharyngeal carcinoma and esophagus cancer, and 1 case of pharyngeal carcinoma complicated with rectal cancer. Conclusion the detection rate of early laryngopharyngeal carcinoma before NBI magnification endoscopy is better than that of white light endoscopy, but there is no difference between NBI endoscopy and white light endoscopy in the diagnosis of advanced pharyngolaryngeal carcinoma. Special attention should be paid to the simultaneous presence of pharyngeal and esophageal cancer in the examination.
【作者单位】：第三军医大学新桥医院消化内科;
【分类号】：R739.6

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