30例外耳道、中耳恶性肿瘤的临床分析
发布时间：2018-11-17 20:26
【摘要】：目的 探讨外耳道、中耳恶性肿瘤的临床表现、诊断要点及治疗原则和方法,以期提高患者生存率,改善生活质量。 方法 回顾性分析2000年1月-2009年1月郑州大学第一附属医院耳鼻咽喉头颈外科收治并经病理证实的资料完整的外耳道、中耳恶性肿瘤30例,分析内容包括临床表现、病理类型、影像学表现、颈部淋巴结B超及其他辅助检查,不同临床分期及不同治疗方案的预后,定期随访情况等。在定期随访期间做术腔的清理、复查CT或MRI。 结果 全组随访3年累积生存率为77%,5年累积生存率为58.4%,复发多发生在2-5年内。按still系统,在30例患者中T1期6例,T2期15例,T3期9例,早期诊治的患者累积生存较高,预后较好。单纯手术治疗易复发。 结论 1外耳道、中耳恶性肿瘤以鳞状细胞癌和腺样囊性癌多见。 2临床分期较早的患者累积生存率较高,针对不同病例选择合适的治疗方案,早期诊断,早期治疗是提高5年累积生存率的关键。 3以手术为主结合放疗和/或化疗的综合治疗是本病的最佳治疗方案。 4术后长期规范随访,建立长期随访质量,便于提高治疗效果和尽早发现复发的患者。
[Abstract]:Objective to investigate the clinical manifestation, diagnosis and treatment of malignant tumors of external auditory canal and middle ear in order to improve the survival rate and quality of life. Methods from January 2000 to January 2009, 30 cases of external auditory canal and middle ear malignant tumor treated in Department of Otorhinolaryngology and head and neck surgery of the first affiliated Hospital of Zhengzhou University were retrospectively analyzed. Pathological types, imaging findings, cervical lymph node B ultrasound and other auxiliary examination, different clinical stages and treatment of the prognosis, regular follow-up and so on. Perform surgical cavity cleaning during regular follow-up and review CT or MRI. Results the 3-year cumulative survival rate and 5-year cumulative survival rate were 77 and 58.4 respectively. Recurrence occurred within 2-5 years. According to still system, there were 6 cases of T1 stage, 15 cases of T2 stage and 9 cases of T3 stage in 30 cases. The patients with early diagnosis and treatment had higher cumulative survival and better prognosis. Simple surgical treatment is easy to relapse. Conclusion 1 squamous cell carcinoma and adenoid cystic carcinoma are the most common malignant tumors in external auditory canal and middle ear. (2) the cumulative survival rate of the patients with earlier clinical stages was higher. The key to improve the 5-year cumulative survival rate was to select appropriate treatment schemes for different cases and to make early diagnosis and early treatment. 3 combined surgery combined with radiotherapy and / or chemotherapy is the best treatment for this disease. (4) long term standard follow-up and quality of long term follow-up were established to improve the effect of treatment and to detect recurrence as soon as possible.
【学位授予单位】：郑州大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R764
本文编号：2338951
[Abstract]:Objective to investigate the clinical manifestation, diagnosis and treatment of malignant tumors of external auditory canal and middle ear in order to improve the survival rate and quality of life. Methods from January 2000 to January 2009, 30 cases of external auditory canal and middle ear malignant tumor treated in Department of Otorhinolaryngology and head and neck surgery of the first affiliated Hospital of Zhengzhou University were retrospectively analyzed. Pathological types, imaging findings, cervical lymph node B ultrasound and other auxiliary examination, different clinical stages and treatment of the prognosis, regular follow-up and so on. Perform surgical cavity cleaning during regular follow-up and review CT or MRI. Results the 3-year cumulative survival rate and 5-year cumulative survival rate were 77 and 58.4 respectively. Recurrence occurred within 2-5 years. According to still system, there were 6 cases of T1 stage, 15 cases of T2 stage and 9 cases of T3 stage in 30 cases. The patients with early diagnosis and treatment had higher cumulative survival and better prognosis. Simple surgical treatment is easy to relapse. Conclusion 1 squamous cell carcinoma and adenoid cystic carcinoma are the most common malignant tumors in external auditory canal and middle ear. (2) the cumulative survival rate of the patients with earlier clinical stages was higher. The key to improve the 5-year cumulative survival rate was to select appropriate treatment schemes for different cases and to make early diagnosis and early treatment. 3 combined surgery combined with radiotherapy and / or chemotherapy is the best treatment for this disease. (4) long term standard follow-up and quality of long term follow-up were established to improve the effect of treatment and to detect recurrence as soon as possible.
【学位授予单位】：郑州大学
【学位级别】：硕士
【学位授予年份】：2011
【分类号】：R764
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