北京市三级综合医院门诊抗生素使用情况分析

发布时间：2018-01-24 02:33

本文关键词： 北京市三级综合医院抗生素 DDDs DUI　出处：《现代预防医学》2017年05期 　论文类型：期刊论文

【摘要】：目的了解北京市三级综合医院合理使用抗生素的情况,为促进抗生素的有效管理与合理应用提供依据。方法随机抽取北京市13家三级综合医院,收集2014.1~2015.12门诊处方数据,分析抗生素处方占比、使用金额、注射用抗生素占比、抗生素联合使用率、DDDs(用药频度,frequency of drug use)和DUI(药物利用指数,drug use index)等指标。结果 2014和2015年,北京市三级综合医院门诊抗生素处方占比分别为3.00%和2.79%,注射用抗生素占比分别为24.01%和21.67%,抗生素联合使用率分别为7.78%和7.51%,且三甲医院均高于非三甲医院;用药金额和用药频度排名靠前的多为广谱的二、三代头孢菌素;发现注射用阿莫西林钠舒巴坦钠、注射用头孢米诺钠、注射用头孢他啶DUI1。结论北京市三级综合医院门诊抗生素使用的合理性总体较好,对其中的非三甲医院应重点监测;广谱抗生素的大量使用应当引起重视;注射用阿莫西林钠舒巴坦钠、注射用头孢米诺钠、注射用头孢他啶三种抗生素用药频度偏高,应予以重点管理。
[Abstract]:Objective to understand the rational use of antibiotics in Beijing tertiary general hospitals and to provide the basis for promoting the effective management and rational application of antibiotics. Methods 13 tertiary general hospitals in Beijing were randomly selected. The data of outpatient prescriptions were collected from April 1, 2011 to December, 2015.The proportion of prescriptions of antibiotics, the amount of money used, the proportion of antibiotics for injection, the combined use rate of antibiotics and DDDswere analyzed. Frequency of drug use) and DUI (drug use index). Results 2014 and 2015. The proportions of antibiotics prescriptions and injection antibiotics were 3.00% and 2.79, 24.01% and 21.67%, respectively. The combined use rate of antibiotics was 7.78% and 7.51 respectively. The second and third generation cephalosporins ranked first in the amount and frequency of drug use; It was found that amoxicillin sodium for injection sulbactam sodium for injection cefminox sodium for injection and ceftazidime for injection DUI1.Conclusion the rational use of antibiotics in outpatient clinic of Beijing tertiary general hospital is good in general. Among them, non-triple A hospitals should focus on monitoring; Attention should be paid to the extensive use of broad-spectrum antibiotics. Amoxicillin sodium for injection, sulbactam sodium for injection, cefminox sodium for injection and ceftazidime for injection are more frequently used.
【作者单位】：北京大学公共卫生学院卫生政策与管理系;
【分类号】：R978.1
【正文快照】： 自1940年青霉素开始用于治疗以来,抗生素不断发展,无论从品种、数量还是金额上在总药品使用中都占有重要地位。但无指证用药、联合用药、滥用广谱抗生素[1]等抗生素不合理使用抗生素导致耐药性的问题也日趋严重。2014年WHO发布首份全球抗生素耐药报告[2]显示,在西太平洋地区,

【参考文献】