利用循证药学规范超说明书用药的工作实践

发布时间：2018-05-06 01:44

  本文选题：超药品说明书用药 + 循证药学　； 参考：《中国医院药学杂志》2017年13期

【摘要】：目的:利用循证药学模式规范超说明书用药,为临床合理的超说明书用药提供依据,对不合理的使用给予预警或干预。方法:临床药师2015年每月随机抽取某院门诊处方100份,对有超说明书用药的处方进行分类统计,并通过中外数据库、典籍、指南等循证依据,依照证据质量提出超说明书用药的推荐强度和干预措施。结果:抽调的1 200份处方中有50.08%的处方存在超说明书用药,超说明书用法的分类及各分类所占总处方的比例分别为超用法用量(24.25%)、超适应证用药(13.75%)和超适用人群(12.08%)。对所涉及的23类超说明书使用药品循证分析后,为医生提供了3种公认有益(Ⅰ级推荐)的超说明书用法,并且对10类Ⅱb/Ⅲ级推荐的超说明书用药进行干预,共有6类超说明书用法在处方干预前后得到明显的改善。结论:利用循证药学方法不仅可以为医生合理的超说明书用药提供保障,更有助于医生接受和采纳临床药师的合理建议,减少超说明书用药风险。
[Abstract]:Objective: to provide evidence for rational drug use in clinical practice and to provide early warning or intervention for irrational use. Methods: in 2015, the clinical pharmacists randomly selected 100 prescriptions from outpatient clinics in a certain hospital in 2015, and classified the prescriptions with overprescriptions, and used the evidence bases of Chinese and foreign databases, classics, guidelines, etc. According to the quality of evidence, the recommended strength and intervention measures of the drug were put forward. Results: 50.08% of the 1 200 prescriptions were superprescriptions. The proportion of overdose and the proportion of each classification to the total prescriptions were 24.25%, 13.75% and 12.08%, respectively. Evidence-based analysis of the 23 kinds of superscript involved provided doctors with 3 kinds of superscript usages that were recognized as beneficial (grade 鈪，

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