上海地区22家医院2013-2015年带状疱疹患者药物应用分析

发布时间：2018-11-05 16:33

【摘要】：目的:了解上海地区22家医院带状疱疹患者的药物应用情况及趋势,为临床合理用药提供参考。方法:对上海地区22家医院2013-2015年带状疱疹患者使用药物的人次占比、销售金额、用药频度(DDDs)、日均费用(DDC)等数据进行统计分析。结果:带状疱疹多发于成人,集中于45岁以上人群(75%)。神经营养药、抗疱疹病毒药、抗神经痛药使用人次占比排在前3位,局部治疗药、免疫调节药及糖皮质激素亦占一定比例。抗病毒药中,伐昔洛韦各年度的销售金额和DDDs均列第1位,溴夫定的DDC最高;抗神经痛药中,使用人次占比最高的是抗癫痫药(13.78%),其复合增长率也最高(30.77%),其中使用人次最多的药品为加巴喷丁;神经营养药中,使用人次占比最高的是甲钴胺(32.98%);免疫调节药中,胸腺法新的使用人次最多,可能存在不合理应用情况。结论:上海地区带状疱疹药物治疗方案基本符合相关治疗指南,但免疫调节药的不合理应用等问题仍需引起关注并进行监管。
[Abstract]:Objective: to investigate the application and trend of herpes zoster in 22 hospitals in Shanghai. Methods: 22 hospitals in Shanghai from 2013 to 2015 were statistically analyzed on the proportion of patients using herpes zoster, the sum of money sold, the daily average cost of (DDDs), and so on. Results: herpes zoster was more common in adults than 45 years old (75%). Neurotrophic drugs, anti-herpes virus drugs, anti-neuralgia drugs were used in the first three places, local treatment drugs, immunomodulatory drugs and glucocorticoids also accounted for a certain proportion. Among antiviral drugs, valaciclovir was ranked first in sales amount and DDDs in each year, and Bromovudine was the highest in DDC; Among the antineuralgia drugs, the antiepileptic drugs (13.78%) were used most frequently, and the compound growth rate was the highest (30.77%), among which the most commonly used drugs were gabapentin. Among the neurotrophic drugs, mecobalamin (32.98%) was the most frequently used, and the thymus method was the most frequently used among the immunomodulators, which might lead to unreasonable use. Conclusion: the drug therapy for herpes zoster in Shanghai area basically accords with the related treatment guidelines, but the irrational use of immunomodulatory drugs still needs to be paid attention to and supervised.
【作者单位】：上海市皮肤病医院药剂科;
【分类号】：R969.3

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