临床药师在抗菌药物临床应用管理中的作用

发布时间：2019-04-24 07:52

【摘要】：目的:探讨临床药师在抗菌药物临床应用管理中的作用。方法:选择2013年7月至2013年12月鹤山市人民医院患者420例,随机分为两组,每组210例,设定观察组为临床药师干预抗菌药物使用组,对照组为无干预使用抗菌素组,比较两组不合理用药情况、不良反应、住院时间以及抗菌药物使用频次排序前5位统计,同时对患者药物联用情况进行记录。结果:观察组不合理用药率16.7%少于对照组83.8%,不良反应发生率4.8%少于对照组21.0%,住院时间(4.01±0.85)d少于对照组(12.13±3.46)d,差异具有统计学意义(P0.05);观察组青霉素类药物和第1、2代头孢菌素类药物使用率明显升高,而奥硝唑的使用频次明显减少;观察组一联、二联、三联用药分别为75.2%、20.0%、4.8%,对照组为53.8%、32.9%、13.3%,观察组较对照组一联用药多,二联、三联用药少,差异具有统计学意义(P0.05)。结论:临床药师在抗菌药物临床应用管理中作用明显,有效提高住院治疗效率,减少不良反应,降低滥用抗生素现象发生率。
[Abstract]:Objective: to explore the role of clinical pharmacists in the management of clinical application of antibacterial drugs. Methods: from July 2013 to December 2013, 420 patients in Heshan people's Hospital were randomly divided into two groups, 210 cases in each group. The observation group was clinical pharmacist intervention group and the control group was no intervention group. The first 5 statistics of unreasonable drug use, adverse reactions, hospitalization time and frequency of antimicrobial use were compared between the two groups, and the combined use of drugs was recorded at the same time. Results: the rate of unreasonable drug use in the observation group was lower than that in the control group (83.8%), the incidence of adverse reactions was 4.8% less than that in the control group (21.0%), and the hospitalization time was (4.01 卤0.85) days less than that in the control group (12.13 卤3.46) days. The difference was statistically significant (P0.05); In the observation group, the use rate of penicillin drugs and the first and second generation cephalosporins increased significantly, while the use frequency of ornidazole decreased significantly. The first, second and third drugs were 75.2%, 20.0%, 4.8% in observation group, 53.8%, 32.9%, 13.3% in control group, respectively. The difference was statistically significant (P0.05). Conclusion: the clinical pharmacists play an important role in the management of the clinical application of antibiotics, which can effectively improve the efficiency of hospitalization, reduce the adverse reactions and reduce the incidence of the abuse of antibiotics.
【作者单位】：鹤山市人民医院;
【分类号】：R95

【相似文献】