Pickering乳液法制备有机—无机复合功能性微球

发布时间：2018-01-24 01:47

  本文关键词： Pickering乳液 温敏性 pH敏感性 磁性 复合空心微球　出处：《北京化工大学》2011年硕士论文　论文类型：学位论文

【摘要】：有机-无机复合空心微球是一种具有特殊结构的新型复合材料。复合空心微球可以使有机聚合物的优点及无机物的优点得到更好的结合,从而使有机-无机复合空心微球获得多种特有的性能。有机-无机复合空心微球在医药,环保及生物化工等领域都有着广阔的应用前景。因此,本文采用Pickering乳液模板法制备了聚N-异甲基丙烯酰胺/二氧化硅复合微胶囊,聚a-甲基丙烯酸/二氧化硅复合微胶囊和磁性壳聚糖复合空心微球,并对其制备的影响因素,形成机理以及应用做了系统的研究。具体内容如下： 1.以KH-570改性二氧化硅为稳定剂,以温敏性单体N-异丙基丙烯酰胺和聚N-异丙基丙烯酰胺的水溶液作为水相,以液态石蜡作为油相,制备了反相Pickering乳液,经过聚合,制备了具有温度敏感性的聚N-异甲基丙烯酰胺/二氧化硅复合微胶囊。温敏性微胶囊的平均粒径约为7-10μm,微胶囊壁是由温敏性聚合物和二氧化硅共同组成的,并且在不同温度条件下研究了温敏性微胶囊的缓释性能,当缓释温度由25℃升高到45℃时,温敏性微胶囊中罗丹明B的总释放量由25.7%提高到了70.9%。 2.以KH-570改性二氧化硅为稳定剂,以α-甲基丙烯酸水溶液作为水相,以液态石蜡作为油相制备了反相Pickering乳液,再通过聚合制备了具有pH敏感性的聚α-甲基丙烯酸/二氧化硅复合微胶囊。复合微胶囊具有良好的pH敏感性能,平均粒径约为7-101μm,微胶囊壁是由pH敏感性聚合物和二氧化硅共同组成的,壁厚约为1μm, pH敏感微胶囊在酸、碱两种介质中罗丹明B的释放量分别为15.0%和98.4%。 3.以油酸改性纳米四氧化三铁为稳定剂,以液体石蜡为油相,壳聚糖的醋酸水溶液作为水相,采用反相Pickering乳液模板法制备了磁性壳聚糖复合空心微球,微球的平均粒径约为8μm,壁厚为80nm,并使用红外,热重等对其进行表征。
[Abstract]:The organic-inorganic composite hollow microspheres are a new type of composite material with special structure. The advantages of organic polymers and inorganic materials can be better combined by composite hollow microspheres. Therefore, the organic-inorganic composite hollow microspheres have a wide application prospect in medicine, environmental protection and biochemical fields. In this paper, Pickering emulsion template method was used to prepare poly (N-isomethacrylate) / silica composite microcapsules. Poly (a- methacrylic acid / silica) composite microcapsules and magnetic chitosan hollow microspheres were prepared, and the factors affecting their preparation, formation mechanism and application were systematically studied. 1. Using KH-570 modified silica as stabilizer, the aqueous solution of temperature sensitive monomers N isopropyl acrylamide and poly (N isopropyl acrylamide) as water phase and liquid paraffin as oil phase. Inverse Pickering emulsion was prepared and polymerized. Poly (N-isomethacrylamide / silica) composite microcapsules with temperature sensitivity were prepared. The average diameter of the thermo-sensitive microcapsules was about 7-10 渭 m. The microcapsule wall is composed of thermo-sensitive polymer and silica, and the slow-release properties of the thermo-sensitive microcapsule are studied under different temperature conditions, when the slow-release temperature is increased from 25 鈩，

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