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响应面试验优化复凝聚法制备槲皮素微胶囊工艺及其理化性质

发布时间:2018-02-07 14:03

  本文关键词: 槲皮素 复凝聚法 微胶囊 理化性质 出处:《食品科学》2016年22期  论文类型:期刊论文


【摘要】:以槲皮素为芯材,壳聚糖、海藻酸钠为壁材,采用复凝聚法制备槲皮素微胶囊。以包埋率和载药量为综合评价指标,通过单因素试验和响应面试验分析各因素,并对槲皮素微胶囊的理化性质进行研究。结果表明:壁材比(壳聚糖-海藻酸钠质量比)1∶3.34(g/g)、芯壁比4.34∶1(g/g)、京尼平用量18.44 g/100 g壳聚糖、固化温度41.56℃时,包埋率为69.53%。制备的槲皮素微胶囊水分含量为3.26%,休止角为40.39°,溶解度为256.44μg/m L,粒径大小较为均匀,平均粒径为1 362 nm,具有较好的溶解性和稳定性。
[Abstract]:Using quercetin as core material, chitosan and sodium alginate as wall materials, quercetin microcapsules were prepared by complex coagulation method. The physicochemical properties of quercetin microcapsules were studied. The results showed that the ratio of wall to material (mass ratio of chitosan to sodium alginate was 1: 3.34 g / g / g), core / wall ratio was 4.34: 1 g / g / g, amount of genipine was 18.44 g / 100 g chitosan, curing temperature was 41.56 鈩,

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