神经影像大数据与心脑关联:方法学框架与应用

发布时间：2018-01-01 11:30

本文关键词：神经影像大数据与心脑关联:方法学框架与应用　出处：《科学通报》2015年11期 　论文类型：期刊论文

【摘要】：心理科学成为一门成熟科学的必要条件之一是建立心理学概念与神经活动的联系,即心脑关联.当前心脑关联研究通常以心理学概念为出发点形成研究假设,推断脑功能活动特征与心理学概念的关联.心理学概念的形成依赖于观测者的主观经验和一致观念,它们未必反映神经系统的功能组织结构.经过近20年的心脑关联研究,我们仍然难以建立明确而科学的心理学概念与脑活动特征之间的关系.本文综述了当前心脑关联研究的瓶颈、分析其本质原因,并提出以脑为中心、以神经影像大数据为基础的心脑关联研究框架.随后,举例综述新的心脑关联研究框架下神经影像大数据及其方法论.最后,讨论2个实际应用以说明新研究框架对发现心脑关联的独特作用.
[Abstract]:One of the necessary conditions for psychological science to become a mature science is to establish the relationship between psychological concepts and neural activities, that is, the relationship between heart and brain. At present, mental and brain association studies usually take psychological concepts as the starting point to form research hypotheses. The formation of psychological concept depends on the subjective experience and consistent idea of the observer. They do not necessarily reflect the functional structure of the nervous system. It is still difficult to establish a clear and scientific relationship between psychological concepts and the characteristics of brain activity. This paper reviews the bottleneck of the current research on the relationship between the heart and brain, analyzes its essential causes, and puts forward the idea of taking the brain as the center. The research framework of the relationship between the heart and brain based on the neural image big data. Then, an example is given to summarize the big data and its methodology under the new framework of the study of the relationship between the brain and the heart. Finally. Two practical applications are discussed to illustrate the unique role of the new research framework in the discovery of cardiac and brain associations.
【作者单位】：中国科学院心理研究所行为科学重点实验室磁共振成像研究中心人脑功能连接组及其发展实验室;
【基金】：科技支撑计划(2012BAI36B01) 国家自然科学基金(81270023,81278412,81171409,81000583,81220108014) 中国科学院“百人计划” 中国科学院重点部署项目(KSZD-EW-TZ-002) 北京市精神疾病诊断和治疗重点实验室(2014JSJB03) 中国科学院心理研究所杰出青年人才基金(Y4CX062008)资助
【分类号】：B845.1
【正文快照】： *联系人,E-mail:yangz@psych.ac.cn;zuoxn@psych.ac.cn科技支撑计划(2012BAI36B01)、国家自然科学基金(81270023,81278412,81171409,81000583,81220108014)、中国科学院“百人计划”、中国科学院重点部署项目(KSZD-EW-TZ-002)、北京市精神疾病诊断和治疗重点实验室(2014JSJB03

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