急性应激:诱发范式、测量指标及效果分析

发布时间：2018-05-11 11:35

本文选题：急性应激 + 诱发范式　；参考：《心理科学进展》2017年10期

【摘要】：近年来应激研究正逐步成为多学科共同关注的前沿领域。应激诱发范式多样,诱发效果不一致,研究结论无法比较,是目前实验室应激研究面临的最主要问题。本文从快/慢反应通道激活、唾液皮质醇浓度变化,以及脑区激活等方面比较了不同范式的诱发效果。生理性诱发范式更早引起SNS的兴奋,主要激活脑干区域;心理性诱发范式有效引起HPA轴的兴奋,激活前额叶皮层和边缘系统;复合型诱发范式有效引起双通道激活。从联合快慢反应通道检测指标的思路制定应激研究的评估框架,既有利于实现不同范式之间的横向比较,也能够揭示个体应激反应中两系统协同作用的动态平衡机制。
[Abstract]:In recent years, stress research has gradually become a frontier field of common attention. The most important problem in laboratory stress research is the diversity of stress-induced paradigms, the inconsistency of induced effects, and the incomparision of research conclusions. The induction effects of different paradigms were compared in terms of fast / slow response channel activation, salivary cortisol concentration change, and brain activation. Physiological evoked paradigm induced SNS excitatory earlier, mainly activated brain stem region; psychological evoked paradigm effectively induced HPA axis excitement, activated prefrontal cortex and limbic system; compound evoked paradigm effectively caused double-channel activation. Establishing a framework for assessment of stress studies from the perspective of combined fast and slow response channel detection can not only help to achieve horizontal comparison between different paradigms but also reveal the dynamic equilibrium mechanism of the synergistic action of two systems in individual stress response.
【作者单位】：陕西师范大学现代教学技术教育部重点实验室;
【基金】：教育部人文社会科学研究一般项目(16YJC190004) 国家自然科学基金项目(31470977) 陕西师范大学人文社会科学学术帮扶基金项目
【分类号】：B845

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