耐药结核病现状及影响因素研究进展

发布时间：2018-01-20 07:08

本文关键词： 耐药结合病现状影响因素研究进展　出处：《中国医疗设备》2016年S1期 　论文类型：期刊论文

【摘要】：目的探讨我国耐药结核病现状、影响耐药菌出现的因素。方法选取2014年4月至2016年4月本地结核病耐药监测资料中痰结核菌培养阳性肺结核患者500例,对其阳性菌株进行菌型鉴定及异烟肼、利福平、乙胺丁醇和链霉素敏感性测试,据此分析本地耐药结核病现状及影响因素。结果全500例阳性患者中,结核分支杆菌复合群435例(87.0%),非结核分枝杆菌65例(13.0%),总耐药率30.34%,耐多药率8.25%,新发患者的耐药率为28.0%,耐多药率为6.25%,复治患者的耐药率为57.14%,耐多药率为22.86%。经单因素及多因素分析,进行抗结核治疗是导致结核病患者耐药出现的主要原因。结论对结核病患者进行治疗时,应进行菌株敏感试验确定治病菌株及有效的治疗药物后再行治疗,以减少患者出现耐药的几率。
[Abstract]:Objective to investigate the current situation of drug-resistant tuberculosis in China. Methods from April 2014 to April 2016, 500 tuberculosis patients with positive sputum tuberculous bacteria culture were selected. The positive strains were identified and tested for isoniazid, rifampicin, ethambutanol and streptomycin. There were 435 cases of mycobacterium tuberculosis complex group and 65 cases of non-tuberculosis mycobacterium tuberculosis. The total drug resistance rate was 30.34 and the multidrug resistance rate was 8.25%. The drug resistance rate of the newly developed patients was 28.0, the multidrug resistance rate was 6.25, the drug resistance rate of the patients with re-treatment was 57.14 and the multi-drug resistance rate was 22.86.The single factor and multi-factor analysis were used. Anti-tuberculosis therapy is the main cause of drug resistance in tuberculosis patients. Conclusion when TB patients are treated, strain sensitivity test should be carried out to determine the treatment strains and effective treatment drugs should be performed after treatment. To reduce the risk of drug resistance in patients.
【作者单位】：河北省唐山市第四医院;
【分类号】：R52
【正文快照】： 结核病是目前全世界面临的严重公共卫生问题,因为耐药菌株的产生,导致临床对于该疾病的治疗困难,因为疾病具有传染性,如不及时进行疾病的治疗及疫情控制,常对社会造成严重危害,故对结核菌耐药菌株出现的原因进行研究,对于有效控制疾病的传播意义重大[1]。为了研究我国耐药结核

【相似文献】