解毒凉血法治疗乙型肝炎加急性肝衰竭的疗效评价及机制研究

发布时间：2018-04-03 15:17

  本文选题：乙型肝炎　切入点：急性肝衰竭　出处：《中华中医药学刊》2017年06期

【摘要】：目的:探析乙型肝炎加急性肝衰竭病症在解毒凉血治疗下的临床疗效。方法:将2014年12月—2015年12月于医院接受治疗的90例乙型肝炎加急性肝衰竭患者选为分析的对象,并随机将其分均为对照组与观察组,对照组予以西药治疗,观察组在对照组的基础上予以解毒凉血法治疗,比较两组患者的临床疗效、肝功能(凝血酶原活动度(PTA)、总胆红素(TBIL)、血清白蛋白(ALB))情况、并发症的发生情况等。结果:观察组的治疗总有效率(97.78%)高于对照组(75.56%),肝功能指标:PTA(74.25±10.20)%、TBIL(121.85±30.10)μmol/L、ALB(45.56±6.23)g/L指标均较对照组的PTA(50.45±10.25)%、TBIL(242.65±30.15)μmol/L、ALB(32.78±6.10)g/L指标趋于正常值,且并发症的发生率(6.67%)低于对照组(35.56%),比较的结果均具有统计学意义(P0.05)。结论:乙型肝炎加急性肝衰竭病症在解毒凉血治疗下的疗效尤为显著,不仅可以有效地改善患者的肝功能,而且降低并发症的发生率,值得临床广泛应用。
[Abstract]:Objective: to explore the clinical effect of hepatitis B combined with acute liver failure in the treatment of detoxification and cooling blood.Methods: 90 patients with hepatitis B and acute liver failure who were treated in hospital from December 2014 to December 2015 were selected as the objects of analysis. The patients were randomly divided into control group and observation group, the control group was treated with western medicine, and the control group was treated with western medicine.The observation group was treated with the method of detoxification and cooling blood on the basis of the control group. The clinical curative effect, liver function (prothrombin activity, total bilirubin TBILN, serum albumin and ALBN), and the occurrence of complications were compared between the two groups.缁撴灉:瑙傚療缁勭殑娌荤枟鎬绘湁鏁堢巼(97.78%)楂樹簬瀵圭収缁，

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