29例成人EB病毒感染不同预后的临床特征分析比较

发布时间：2018-05-10 07:03

本文选题：EB病毒感染 + 临床特征　；参考：《重庆医科大学学报》2017年07期

【摘要】：目的:分析比较我院无基础疾病的成人Epstein-Barr(EB)病毒感染不同预后的临床特征,以指导临床诊治。方法:回顾性分析我院2014年12月至2016年6月确诊的成人EB病毒感染患者的临床资料、实验室检查和诊治情况,比较分析预后较好的与预后较差患者的临床特征。结果:在29例无基础疾病的成人EB病毒患者中,主要表现为26例发热,18例咽痛,22例淋巴结肿大,15例扁桃体肿大,4例肝大,8例脾大,14例白细胞升高和19例谷丙转氨酶升高等。预后较好的疾病患者年龄较小(P=0.001),更多见咽痛、扁桃体肿大(P=0.004),预后较差疾病的患者更多见红细胞减少(P=0.000)和血红蛋白降低(P=0.001)。常见的并发症为肝损害,不同的年龄在有肝损害与无肝损害患者之间有差异。结论:在无基础疾病的成人EB病毒感染中,不同预后的临床特征有差异,预后较好的疾病患者年龄较小,多为青少年,多见咽痛、扁桃体肿大,预后较差疾病患者多为中老年,易发生二系血细胞减少。
[Abstract]:Objective: to analyze and compare the different prognosis of Epstein-Barrna virus infection in adults without underlying diseases in our hospital. Methods: the clinical data, laboratory examination, diagnosis and treatment of adult patients with EB virus infection from December 2014 to June 2016 were analyzed retrospectively. The clinical features of patients with better prognosis and worse prognosis were compared and analyzed. Results: in 29 adult EBV patients without underlying diseases, 26 cases of fever and 18 cases of pharyngitis 22 cases of lymphadenomegaly 15 cases of tonsillectomy, 4 cases of hepatomegaly, 8 cases of splenomegaly, 14 cases of leukocyte elevation and 19 cases of elevated glutamic pyruvic transaminase, etc. In the patients with better prognosis, the patients with better prognosis were more likely to have pharyngitis and tonsillar enlargement. The patients with poor prognosis were more likely to see erythrocytopenia (0.000) and hemoglobin decreased (P < 0.001). The common complication was liver damage, which varied in age between patients with and without liver damage. Conclusion: in adult patients with EBV infection without underlying diseases, the clinical characteristics of different prognosis are different. The patients with better prognosis are younger, more adolescents, more pharyngitis, enlarged tonsils, and older patients with poor prognosis. Second line blood cell decline is easy to occur.
【作者单位】：重庆医科大学第二附属医院感染科;
【分类号】：R512.99

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