血府逐瘀汤联合恩替卡韦治疗慢性乙型肝炎肝纤维化60例

发布时间：2018-05-25 00:35

  本文选题：慢性乙型肝炎 + 肝纤维化　； 参考：《河南中医》2016年01期

【摘要】：目的:观察血府逐瘀汤联合恩替卡韦治疗慢性乙型肝炎肝纤维化的临床疗效。方法:将60例慢性乙型肝炎肝纤维化患者随机分为对照组和观察组,每组各30例。对照组应用恩替卡韦治疗,观察组在对照组的基础上联合血府逐瘀汤。观察两组患者的临床疗效及治疗前后肝纤维化指标的变化情况。结果:观察组有效率为90.00%,对照组有效率为63.33%,两组有效率比较,差异具有统计学意义(P0.05)。两组患者治疗前肝纤维化指标差异无统计学意义(P0.05)。治疗后两组患者血清透明质酸(hyaluronic acid,HA)、层粘蛋白(laminin,LN)、Ⅲ型前胶原PCⅢ、Ⅳ型胶原Ⅳ-C各项指标均较治疗前显著降低,且观察组优于对照组,差异具有统计学意义(P0.05)。结论:血府逐瘀汤联合恩替卡韦治疗慢性乙型肝炎肝纤维化临床疗效显著,且能改善患者肝纤维化水平。
[Abstract]:Objective: to observe the clinical effect of Xuefu Zhuyu decoction combined with entecavir on chronic hepatitis B liver fibrosis. Methods: 60 patients with chronic hepatitis B liver fibrosis were randomly divided into control group and observation group with 30 cases in each group. The control group was treated with entecavir, and the observation group combined with Xuefu Zhuyu decoction on the basis of the control group. To observe the clinical effect of the two groups and the changes of hepatic fibrosis indexes before and after treatment. Results: the effective rate was 90.00g in the observation group and 63.33 in the control group. The difference between the two groups was statistically significant (P 0.05). There was no significant difference in hepatic fibrosis between the two groups before treatment (P 0.05). After treatment, the serum hyaluronic acidonium, laminin (LNN), procollagen 鈪，

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