1995-2013年上海市静安区HIV感染者诊断延迟状况研究
发布时间:2018-05-30 17:17
本文选题:HIV感染 + 诊断 ; 参考:《中华疾病控制杂志》2015年04期
【摘要】:目的研究上海市静安区人类免疫缺陷病毒(human immunodeficiency virus,HIV)感染者中诊断延迟的比例及危险因素。方法收集静安区自首次报告(1995年)至2013年管理的HIV感染者和艾滋病病人,研究被动检测的病例所占比例及人群特征,分别计算"延迟报告"(late presentation,LP)和"伴进展性HIV感染的报告"(presentation with advanced HIV disease,PAHD)的比例并进行危险因素分析。结果 630例感染者和病人纳入研究。227例(36.0%)为被动检测,年龄≥50岁(OR=2.767,95%CI:1.661~4.612)是被动检测的危险因素,而同性传播(OR=0.321,95%CI:0.220~0.469)是被动检测的保护因素。588例(93.3%)病人的诊断延迟情况明确:其中LP为353例(60.0%),PAHD为212例(36.1%)。被动检测是LP(OR=1.659,95%CI:1.127~2.442)和PAHD(OR=2.035,95%CI:1.392~2.974)的危险因素,而同性传播(OR=0.630,95%CI:0.424~0.938)是PAHD的保护因素。结论静安区HIV感染者和艾滋病病人诊断延迟情况较严重,被动检测确诊的病例更容易出现诊断延迟。目前亟需创新的防控策略和措施来加强HIV感染者的早期检测。
[Abstract]:Objective to study the proportion and risk factors of delayed diagnosis of HIV infected with human immunodeficiency virus (immunodeficiency) in Jing'an District of Shanghai. Methods the proportion and population characteristics of HIV infected persons and AIDS patients who were managed from the first report (1995) to 2013 in Jing'an District were studied. The proportion of late presentation LPs and presentation with advanced HIV disease with progressive HIV infection were calculated and the risk factors were analyzed. Results in the study of 630 cases of infected persons and patients, 227 cases (36.0) were examined passively, and the age 鈮,
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