女性尖锐湿疣患者宫颈人乳头瘤状病毒和沙眼衣原体感染的流行病学调查

发布时间：2018-08-10 18:05

【摘要】：目的:总结性病门诊女性尖锐湿疣(CA)患者并发泌尿生殖道沙眼衣原体(Ct)的流行病学资料,了解该组患者宫颈有无人乳头瘤状病毒(HPV)感染及HPV基因分型。方法:收集确诊为尖锐湿疣的女性宫颈脱落细胞样本,检测HPV DNA分型及Ct的DNA。结果:123例女性CA患者宫颈样本中HPV、Ct及共同感染率分别是88.6%(109/123)、22.7%(20/88)及22.7%(20/88)。其中高危型HPV感染者占75.6%(93/123),最常见的亚型为HPV-16、52、18、51、58。65.0%(80/123)表现为混合HPV感染;13.0%(16/123)仅为低危HPV感染;10.6%(13/123)仅为高危HPV感染。结论:该组22.7%的CA女性患者宫颈并发Ct感染,88.6%并发宫颈HPV感染,其中高危型达75.6%。在CA女性患者中开展Ct及宫颈HPV检测很有必要。
[Abstract]:Objective: to summarize the epidemiological data of chlamydia trachomatis (Ct) in female patients with condyloma acuminatum (CA) complicated with urogenital tract, and to find out the (HPV) infection and HPV genotyping in cervix of female patients with condyloma acuminatum. Methods: samples of cervical exfoliated cells from women with condyloma acuminatum were collected and HPV DNA typing and Ct DNA were detected. Results the HPVCt and co-infection rates were 88.6% (109 / 123) and 22.7% (20 / 88) in the cervical samples of 123 female patients with CA, respectively. High risk HPV infection accounted for 75.6% (93 / 123), and the most common subtype was HPV-1652O1851T 58.65.0% (80 / 123) with mixed HPV infection of 13.0% (16 / 123), only 10.6% (13 / 123) of low risk HPV infection. Conclusion: in 22. 7% of CA female patients, 88. 6% of them were complicated with Ct infection, and 75. 6% of them had high risk of cervical HPV infection. Ct and cervical HPV are necessary in CA women.
【作者单位】： 天津医科大学总医院皮肤性病科;
【分类号】：R752.53
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