7例艾滋病相关型卡波西肉瘤临床文献分析

发布时间：2018-10-14 13:44

【摘要】：目的总结艾滋病(AIDS)合并卡波西肉瘤病人的临床特征及治疗转归。方法选取北京佑安医院2004年1月至2015年1月收治的7例艾滋病合并卡波西肉瘤病人的病例资料,对其临床特征、治疗以及疾病转归进行回顾性调查分析。结果 7例艾滋病合并卡波西肉瘤病人均为男男性行为者(MSM),年龄中位数为34岁(22~51岁),6例汉族,1例回族。皮肤黏膜均受累,口腔黏膜受累5例,局部淋巴结肿大4例,肺部受累3例,肝脏受累1例,球结膜受累1例。病人CD+4T淋巴细胞计数均200个/mm3,其中6例(85.7%)CD+4T淋巴细胞100个/mm3。5例病人治疗后病情均好转,其中4例病人应用抗反转录病毒治疗(ART)联合全身化疗,1例病人单用ART,2例病人放弃治疗后死亡。结论 MSM中艾滋病晚期合并卡波西肉瘤的病人,如不进行治疗预后极差,部分病人单独应用ART病灶即可消退,病变广泛者联合全身化疗疗效较好。
[Abstract]:Objective to summarize the clinical features and outcome of (AIDS) with Kaposi's sarcoma. Methods from January 2004 to January 2015, 7 cases of AIDS complicated with Kaposi's sarcoma were collected and analyzed retrospectively. Results the median age of (MSM), in 7 AIDS patients with Kaposi's sarcoma was 34 years old (22 ~ 51 years), 6 Han nationality and 1 Hui nationality. Skin and mucosa were all involved, oral mucosa was involved in 5 cases, local lymphadenopathy in 4 cases, lung involvement in 3 cases, liver involvement in 1 case, bulbar conjunctiva involvement in 1 case. The counts of CD 4T lymphocytes in all patients were 200 / mm3, 6 cases (85.7%) CD 4T lymphocytes per mm3.5 patients were all improved after treatment. Four patients were treated with antiretrovirus combined with systemic chemotherapy for (ART), and one patient died after giving up treatment with ART,2 alone. Conclusion in MSM patients with advanced AIDS complicated with Kaposi's sarcoma, if the prognosis is very poor, some patients can recede with ART alone, and the patients with extensive disease combined with systemic chemotherapy have better curative effect.
【作者单位】：首都医科大学附属北京佑安医院感染中心;东营市人民医院感染性疾病科;北京协和医院感染内科;
【基金】：北京市科委艾滋病重大专项(D141100000314005,D141100000314002) 国家艾滋病和病毒性肝炎等重大传染病防治科技“十二五”重大专项(2012ZX10001-003,2012ZX10001-006)~~
【分类号】：R512.91

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