四川省钩端螺旋体病高发县报告病例的准确性调查研究

发布时间：2018-11-28 12:45

【摘要】：目的了解四川省钩端螺旋体病高发地区报告钩体病例准确性,为进一步控制钩体病流行提供科学依据。方法采集2012年钩体病高发地区报告临床诊断病例血清进行钩体菌培养,血清学诊断,对钩体病检测结果为阴性的标本进行乙脑、出血热和立克次体检测。结果共采集87例报告病例的血清标本,培养出4株钩体菌,钩体菌培养阳性率为4.6%。采集64份病例急性期和恢复期双份血清进行钩体病检测,其中54例阳性,阳性率为84.4%,采集23份病例单份血清,其中6份钩体菌检测阳性,阳性率为26.1%。对27份钩体检测阴性标本进行乙脑ELISA检测,阳性1例,出血热、立克次体检测结果均为阴性。结论四川省钩体病高发地区临床诊断钩体病准确性较高,但依然需要加强病例双份血清采集和检测。
[Abstract]:Objective to investigate the accuracy of reporting leptospirosis cases in high incidence areas of Leptospira in Sichuan Province, and to provide scientific basis for further control of leptospirosis. Methods the serological diagnosis of leptospirosis in the high incidence area of leptospirosis in 2012 was carried out by serological diagnosis. The samples with negative results of leptospirosis were tested for je, hemorrhagic fever and Rickettsia. Results A total of 87 serum samples of reported cases were collected and 4 strains of Leptospira were cultured. The positive rate of Leptospira culture was 4.6%. In 64 cases of acute and convalescent stage, 54 cases were positive for leptospirosis, the positive rate was 84.4, and 23 cases were single serums, 6 of them were positive for Leptospira, the positive rate was 26.1%. In 27 samples with negative Leptospira test, the results of ELISA were positive in 1 case, hemorrhagic fever and Rickettsia were all negative. Conclusion the accuracy of clinical diagnosis of leptospirosis in Sichuan Province is high, but it is still necessary to strengthen the collection and detection of double serum samples.
【作者单位】：四川省疾病预防控制中心;中国疾病预防控制中心;
【分类号】：R514.4

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