微酸性电解水对大鼠血液生理生化指标的影响

发布时间：2018-05-28 22:04

本文选题：微酸性电解水 + 血液生理指标　；参考：《中国畜牧杂志》2017年02期

【摘要】：本研究旨在探索微酸性电解水对血液生理指标和血清生化指标的影响。每天给大鼠按每千克体重0、24、31、52、63 mg有效氯(ACC)经口灌胃给药,连续给药30 d。测定大鼠血液白细胞数、红细胞指数、血红蛋白指数、血小板数及肝脏、心脏、肾脏功能血清生化指标。结果表明:随微酸性电解水ACC浓度增加,除嗜碱性粒细胞数变化不规律外,其他白细胞参数都下降(P0.05);随微酸性电解水剂量增加,红细胞数、红细胞压积呈下降趋势(P0.05),平均红细胞体积、红细胞分布宽度标准差、红细胞分布宽度变异系数呈上升趋势(P0.05);微酸性电解水可以促进平均红细胞血红蛋白含量增加(P0.05),但对血红蛋白浓度、平均红细胞体积的影响不规律;微酸性电解水有增加血小板数和血小板压积、降低平均血小板体积和血小板分布宽度的趋势(P0.05);除肌酸激酶有降低趋势外,心脏、肝脏、肾脏功能指标均随给药剂量增加略有升高(P0.05)。结果显示,按每千克体重63mg ACC的微酸性电解水经口灌胃给药,对大鼠血液生理生化指标无显著影响,此剂量下微酸电解水带动物消毒比较安全。
[Abstract]:The purpose of this study was to explore the effect of microacid electrolytic water on blood physiological and serum biochemical indexes. Rats were given orally for 30 days at a dose of 63 mg available chlorine per kilogram of body weight. The white blood cell count, erythrocyte index, hemoglobin index, platelet count and serum biochemical indexes of liver, heart and kidney were measured. The results showed that with the increase of ACC concentration in micro-acid electrolytic water, the number of eosinophils decreased with the increase of the concentration of ACC, and the number of erythrocytes decreased with the increase of the dosage of micro-acid electrolytic water. The hematocrit showed a decreasing trend (P 0.05), the mean volume of red blood cell and the standard deviation of the distribution width of red blood cell. The coefficient of variation in the distribution width of red blood cells showed an increasing trend (P0.05), and the slightly acidic electrolytic water could promote the increase of mean erythrocyte hemoglobin content (P0.05), but the effect on hemoglobin concentration and mean erythrocyte volume was irregular. The microacidic electrolytic water has the tendency of increasing platelet count and platelet pressure, decreasing the mean platelet volume and platelet distribution width (P0.05N), except creatine kinase, the heart and liver, The indexes of renal function increased slightly with the increase of dosage (P 0.05). The results showed that there was no significant effect on blood physiological and biochemical indexes by oral administration of micro-acid electrolytic water per kg BW 63mg ACC in rats. It was safe to disinfect animals with micro-acid electrolytic water at this dose.
【作者单位】：北京农业职业学院;
【基金】：北京市教委科技一般项目(KM201612448002)
【分类号】：S851.36

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