禽类Toll样受体研究进展
发布时间:2018-10-19 13:07
【摘要】:Toll样受体(TLRs)是模式识别受体家族的一员,在天然免疫反应中扮演重要角色。在禽类中至今已发现10种TLRs。研究表明在机体感染病原体时,将激活TLRs并引起一系列抗病毒相关因子的上调,参与宿主抗感染免疫反应。论文主要介绍禽类TLRs的基本特征及抗病毒信号转导通路,同时对TLRs的抗微生物作用进行分析,为TLRs的分子机制研究提供参考。
[Abstract]:Toll-like receptor (TLRs) is a member of the pattern recognition receptor family and plays an important role in innate immune response. Ten species of TLRs. have been found in poultry so far It has been shown that TLRs is activated and a series of antiviral related factors are up-regulated to participate in the host anti-infection immune response when the pathogen is infected. In this paper, the basic characteristics and antiviral signal transduction pathway of avian TLRs are introduced, and the anti-microbial action of TLRs is analyzed, which provides a reference for the study of molecular mechanism of TLRs.
【作者单位】: 哈尔滨师范大学生命科学与技术学院;
【分类号】:S852.4
本文编号:2281205
[Abstract]:Toll-like receptor (TLRs) is a member of the pattern recognition receptor family and plays an important role in innate immune response. Ten species of TLRs. have been found in poultry so far It has been shown that TLRs is activated and a series of antiviral related factors are up-regulated to participate in the host anti-infection immune response when the pathogen is infected. In this paper, the basic characteristics and antiviral signal transduction pathway of avian TLRs are introduced, and the anti-microbial action of TLRs is analyzed, which provides a reference for the study of molecular mechanism of TLRs.
【作者单位】: 哈尔滨师范大学生命科学与技术学院;
【分类号】:S852.4
【参考文献】
相关期刊论文 前1条
1 Yining He;Zhiwen Xie;Jinglong Dai;Yanjie Cao;Jinlian Hou;Yansheng Zheng;Tianchao Wei;Meilan Mo;Ping Wei;;Responses of the Toll-like receptor and melanoma differentiation-associated protein 5 signaling pathways to avian infectious bronchitis virus infection in chicks[J];Virologica Sinica;2016年01期
【共引文献】
相关期刊论文 前2条
1 黄莉;谢芝勋;蓝元喜;谢丽基;邓显文;范晴;罗思思;谢志勤;黄娇玲;张艳芳;王盛;曾婷婷;;禽呼肠孤病毒感染对SPF鸡外周血淋巴细胞中天然免疫相关基因转录的影响[J];畜牧兽医学报;2017年01期
2 何怡宁;戴锦龙;谢智文;曹艳杰;韦平;韦天超;磨美兰;;鸡传染性支气管炎病毒MM41株感染对干扰素调节因子7的影响[J];中国家禽;2016年15期
【二级参考文献】
相关期刊论文 前1条
1 磨美兰;陈秋英;侯金莲;范文胜;李孟;韦平;韦天超;;鸡传染性支气管炎病毒real-time PCR检测方法的建立[J];中国兽医科学;2011年02期
,本文编号:2281205
本文链接:https://www.wllwen.com/yixuelunwen/dongwuyixue/2281205.html