禽类Toll样受体研究进展
发布时间:2018-10-19 13:07
【摘要】:Toll样受体(TLRs)是模式识别受体家族的一员,在天然免疫反应中扮演重要角色。在禽类中至今已发现10种TLRs。研究表明在机体感染病原体时,将激活TLRs并引起一系列抗病毒相关因子的上调,参与宿主抗感染免疫反应。论文主要介绍禽类TLRs的基本特征及抗病毒信号转导通路,同时对TLRs的抗微生物作用进行分析,为TLRs的分子机制研究提供参考。
[Abstract]:Toll-like receptor (TLRs) is a member of the pattern recognition receptor family and plays an important role in innate immune response. Ten species of TLRs. have been found in poultry so far It has been shown that TLRs is activated and a series of antiviral related factors are up-regulated to participate in the host anti-infection immune response when the pathogen is infected. In this paper, the basic characteristics and antiviral signal transduction pathway of avian TLRs are introduced, and the anti-microbial action of TLRs is analyzed, which provides a reference for the study of molecular mechanism of TLRs.
【作者单位】: 哈尔滨师范大学生命科学与技术学院;
【分类号】:S852.4
本文编号:2281206
[Abstract]:Toll-like receptor (TLRs) is a member of the pattern recognition receptor family and plays an important role in innate immune response. Ten species of TLRs. have been found in poultry so far It has been shown that TLRs is activated and a series of antiviral related factors are up-regulated to participate in the host anti-infection immune response when the pathogen is infected. In this paper, the basic characteristics and antiviral signal transduction pathway of avian TLRs are introduced, and the anti-microbial action of TLRs is analyzed, which provides a reference for the study of molecular mechanism of TLRs.
【作者单位】: 哈尔滨师范大学生命科学与技术学院;
【分类号】:S852.4
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,本文编号:2281206
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