国内新型基因2型牛病毒性腹泻病毒研究进展
发布时间：2019-04-02 00:30
【摘要】：牛病毒性腹泻病毒(Bovine viral diarrhea virus,BVDV)有两种基因型:基因1型(BVDV-1)和基因2型(BVDV-2)。以往的流行病学调查显示BVDV-1的分布和流行区域更加广泛,但近年来国内BVDV-2的发病率呈持续升高趋势。BVDV-2通常会引起严重的急性感染和出血综合征,给养牛业造成巨大损失。本文就BVDV-2特异性检测方法和基因分型的建立,型特异性BVDV-2毒株的分离与鉴定,BVDV-2优势分离株的全基因组测定与遗传特性分析及BVDV-1和BVDV-2抗原和抗体检测平台的建立等方面展开简要综述。
[Abstract]:There are two genotypes of bovine viral diarrhea virus (Bovine viral diarrhea virus,BVDV): gene type 1 (BVDV-1) and gene type 2 (BVDV-2). Previous epidemiological investigations showed that the distribution and epidemic areas of BVDV-1 were more extensive, but the incidence of BVDV-2 in China was increasing continuously in recent years. BVDV-2 usually causes severe acute infection and hemorrhage syndrome. Cause a great loss to the cattle industry. In this paper, the establishment of BVDV-2 specific detection method and genotyping, isolation and identification of type-specific BVDV-2 strains, The whole genome determination and genetic characteristics analysis of BVDV-2 dominant isolates and the establishment of detection platforms for BVDV-1 and BVDV-2 antigens and antibodies were briefly reviewed.
【作者单位】： 扬州大学兽医学院;江苏省动物重要疫病与人兽共患病防控协同创新中心;上海市农业科学院畜牧兽医研究所;江苏农牧科技职业学院;
【基金】：科技部畜禽重大疫病防控与高效安全养殖综合技术研发重点专项(2016YFD0500900) 江苏高校优势学科建设工程资助项目 重大动物疫病防控技术引进(国家农业部948计划,2011-G24) 江苏省属高校自然科学重大基础研究项目(14KJA230001) 江苏省农业支撑项目(BE2014358) 泰州市农业科技计划项目(TZ201421)
【分类号】：S852.653
[Abstract]:There are two genotypes of bovine viral diarrhea virus (Bovine viral diarrhea virus,BVDV): gene type 1 (BVDV-1) and gene type 2 (BVDV-2). Previous epidemiological investigations showed that the distribution and epidemic areas of BVDV-1 were more extensive, but the incidence of BVDV-2 in China was increasing continuously in recent years. BVDV-2 usually causes severe acute infection and hemorrhage syndrome. Cause a great loss to the cattle industry. In this paper, the establishment of BVDV-2 specific detection method and genotyping, isolation and identification of type-specific BVDV-2 strains, The whole genome determination and genetic characteristics analysis of BVDV-2 dominant isolates and the establishment of detection platforms for BVDV-1 and BVDV-2 antigens and antibodies were briefly reviewed.
【作者单位】： 扬州大学兽医学院;江苏省动物重要疫病与人兽共患病防控协同创新中心;上海市农业科学院畜牧兽医研究所;江苏农牧科技职业学院;
【基金】：科技部畜禽重大疫病防控与高效安全养殖综合技术研发重点专项(2016YFD0500900) 江苏高校优势学科建设工程资助项目 重大动物疫病防控技术引进(国家农业部948计划,2011-G24) 江苏省属高校自然科学重大基础研究项目(14KJA230001) 江苏省农业支撑项目(BE2014358) 泰州市农业科技计划项目(TZ201421)
【分类号】：S852.653
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