麻鸭感染Ⅰ群禽腺病毒4型的致病及防治研究

发布时间：2019-06-10 08:10

【摘要】：2016年6月,山东省某鸭场养殖的麻鸭在25日龄时发生一种以猝死、心包积液和肝坏死为特征的疾病,死亡率高达40%。通过临床表现,结合PCR检测、鸭腺病毒排查检测、鸡胚传代分离培养、血凝性试验、SPF鸡回归试验与PCR血清型定位分析等实验室检测,确诊该病为Ⅰ群禽腺病毒4型(FAdV-4)感染所致。为有效防控该病,首先注射超免疫卵黄抗体进行治疗,短期内虽然起到了积极的治疗作用,但保护期后该病复发,死亡数量增加,转而采集发病鸭肝组织并进行研磨、灭活,制备组织灭活疫苗,实施紧急免疫,最终成功控制了该病。结果表明,该麻鸭场感染FAdV-4导致发生鸭的心包积水综合征,而同源组织灭活疫苗紧急免疫是防治该病的重要手段。
[Abstract]:In June 2016, a disease characterized by sudden death, pericardial fluid accumulation and liver necrosis occurred in a duck farm in Shandong Province at the age of 25. The mortality rate was as high as 40%. Through clinical manifestations, combined with PCR detection, duck adenovirus detection, chicken embryo subculture, hemagglutination test, SPF chicken regression test and PCR serotyping analysis, etc. The disease was diagnosed as caused by group I avian adenoviral type 4 (FAdV-4) infection. In order to effectively prevent and control the disease, the superimmunized yolk antibody was first injected to treat the disease. Although it played an active therapeutic role in a short period of time, the disease recurred and the number of deaths increased after the protective period, and the liver tissue of the infected duck was collected and ground and inactivated. Tissue inactivated vaccine was prepared and emergency immunization was carried out, and the disease was finally successfully controlled. The results showed that FAdV-4 infection in the duck farm led to pericardial hydrops syndrome in ducks, and emergency immunization with inactivated homologous tissue vaccine was an important means to prevent and cure the disease.
【作者单位】：吉林大学动物医学学院;山东省滨州畜牧兽医研究院;中英禽病国际研究中心;
【基金】：山东省现代农业产业技术体系家禽创新团队项目(SDAIT-11-16)
【分类号】：S858.32

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