颈动脉血液动力学的数值模拟

发布时间：2018-02-16 04:53

本文关键词： 血流动力学颈动脉计算机模拟组织构建组织工程入口条件血液动力学三维模型物理模型 ANSYS 动脉粥样硬化数值模拟　出处：《中国组织工程研究》2014年42期 　论文类型：期刊论文

【摘要】：背景:由于颈动脉个体差异的多样性,血流量的不同等,因此建立人体真实动脉模型有其自身的局限性。目的:分析不同颈总动脉脉动入口波形和内外颈动脉出口流量分配比对颈动脉血液动力学的影响。方法:建立标准性颈动脉音叉式分叉TH-AHCB三维模型。采用不同脉动入口条件和出口流量分配比,利用ANSYS流体分析软件数值模拟颈动脉分叉管内流场,计算血液动力学参数,包括速度、壁面剪切力(WSS)等,结合数值计算结果,不同角度分析其与动脉粥样硬化的关系。结果与结论:内外颈动脉的出口流量分配比的差异对分叉管内的流场影响很大;颈总动脉入口脉动波形的变化不仅改变血液动力学参数(速度、压力、壁面切应力等)的差值,同时还会导致力学机制作用的范围改变。
[Abstract]:Background: because of the diversity of individual differences in carotid artery, the blood flow is not equal. Objective: to analyze the effects of different common carotid artery pulsation inlet waveforms and internal and external carotid flow distribution ratios on carotid hemodynamics. Three-dimensional TH-AHCB model of quasi-carotid tuning fork bifurcation. Different pulsating inlet conditions and outlet flow distribution ratio were used. The ANSYS fluid analysis software was used to simulate the flow field in the carotid bifurcation tube, and the hemodynamic parameters, including velocity, wall shear force and so on, were calculated. Results and conclusion: the difference of flow distribution ratio between internal and external carotid artery has great influence on the flow field in the bifurcation tube. The variation of pulse waveform at the entrance of common carotid artery not only changes the difference of hemodynamic parameters (velocity, pressure, wall shear stress, etc.), but also results in the change of the range of mechanical mechanism.
【作者单位】：浙江大学航空航天学院;
【分类号】：R318.01

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