脾阳虚证动物模型造模方法与模型评价的研究进展

发布时间：2018-04-05 10:18

本文选题：脾阳虚　切入点：大黄　出处：《世界科学技术-中医药现代化》2015年08期

【摘要】：本文通过回顾脾阳虚证模型的造模方法,将其分为模拟传统中医病因的造模方法和现代医学造模方法。目前尚无公认的脾阳虚证造模方法,且主要存在以下问题:现代医学造模方法不符合中医病因病机的规律;模型动物的阳虚症状评价不确切;某些造模方法同时可致其他病症;脾虚证模型的名称混乱不统一;脾阳虚证和脾气虚证的造模方法难以区别等。脾阳虚证模型的评价指标种类繁多,但国内尚未形成标准的模型评价体系。目前,模型评价主要存在以下不规范之处:模型动物的宏观症状缺乏客观量化的评价指标;缺乏中医特色的舌象、脉象;反证方剂的选择不统一;相似的证候未排除;微观指标混乱不成体系等。本文将就脾阳虚证动物模型作一综述。
[Abstract]:This paper reviews the modeling methods of spleen yang deficiency syndrome model and divides it into two kinds of modeling methods: traditional Chinese medicine model method and modern medical model method.At present, there is no accepted method of making model of spleen yang deficiency syndrome, and the main problems are as follows: modern medical model making method does not accord with the law of etiology and pathogenesis of traditional Chinese medicine; the evaluation of model animal's symptoms of yang deficiency is not accurate; some modeling methods can cause other diseases at the same time;The name of spleen deficiency syndrome model is not uniform, and the method of making spleen yang deficiency syndrome and spleen qi deficiency syndrome is difficult to distinguish.There are many kinds of evaluation indexes in spleen yang deficiency syndrome model, but no standard model evaluation system has been formed in our country.At present, there are the following irregularities in the model evaluation: the macroscopic symptoms of the model animals lack objective and quantitative evaluation indicators; the lack of TCM characteristics of tongue, pulse, the choice of anti-syndrome prescription is not uniform; similar syndromes have not been ruled out;The microscopic index is chaotic and out of order.This article will summarize the animal model of spleen yang deficiency syndrome.
【作者单位】：辽宁中医药大学针灸推拿学院;辽宁中医药大学附属医院;
【基金】：科学技术部国家重点基础研究发展计划(2013CB531704):“脾主运化、统血”等脾脏象理论研究,负责人:杨关林
【分类号】：R-332;R228

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